Evidence map›Paper›PMID 24855528›Full record

ReviewInternational journal of stem cells2009

Stem Cells Transplantation and Huntington's Disease.

Wooseok Im, Soon-Tae Lee, Kon Chu, Manho Kim, Jae-Kyu Roh

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of stem cells, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wooseok ImDepartment of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
Soon-Tae LeeDepartment of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea ; Program in Neuroscience, Neuroscience Research Institute of SNUMRC, Seoul National University, Seoul, Korea.
Kon ChuDepartment of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea ; Program in Neuroscience, Neuroscience Research Institute of SNUMRC, Seoul National University, Seoul, Korea.
Manho KimDepartment of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea ; Program in Neuroscience, Neuroscience Research Institute of SNUMRC, Seoul National University, Seoul, Korea.
Jae-Kyu RohDepartment of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea ; Program in Neuroscience, Neuroscience Research Institute of SNUMRC, Seoul National University, Seoul, Korea.
Seoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's disease (HD) is a progressive and devastating neurodegenerative disorder that results in movement abnormalities, cognitive impairments, dementia, and affective disturbances. As no proven medical therapy for this genetic disease is currently available, symptoms mitigation is the primary treatment for HD. Stem cells can play an important role in cell therapy therapeutic strategies to replace dysfunctional or dying cells in HD. Here, we present a brief overview of the current state of stem cells therapy and of the results obtained in animal models of HD, and discuss neuro-protective approaches that utilize stem cells-derived paracrine factors.

Indexed as

Animal modelHuntington’s diseaseStem cells

Identifiers

PMID24855528
PMCPMC4021764
OpenAlexW2105293141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.