Evidence map›Paper›PMID 24855487›Full record

ArticleResearch in autism spectrum disorders2014

Women's posttraumatic stress symptoms and autism spectrum disorder in their children.

Andrea L Roberts, Karestan C Koenen, Kristen Lyall, Alberto Ascherio, Marc G Weisskopf

Abstract read
In one paragraph

Article in Research in autism spectrum disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

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  16. Review
  17. The association between air pollutants and autism spectrum disorders.Environmental science and pollution research international · 2017
    Review
  18. Article
  19. Article
  20. Air Pollution and Autism Spectrum Disorders: Causal or Confounded?Current environmental health reports · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrea L RobertsDepartment of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA.
Karestan C KoenenDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.
Kristen LyallDepartment of Nutrition, Harvard School of Public Health ; University of California, Department of Public Health Sciences, Davis, CA.
Alberto AscherioDepartment of Nutrition, Harvard School of Public Health ; Department of Epidemiology, Harvard School of Public Health.
Marc G WeisskopfDepartment of Epidemiology, Harvard School of Public Health ; Department of Environmental Health, Harvard School of Public Health.
Harvard University · USCalifornia Department of Public Health · USColumbia University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Risk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3M
Genetic Determinants of PTSD in WomenR01MH078928 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C · 2007 to 2010
$2.9M
Prospective Study of Air Pollution and Psychiatric DisordersR21ES019982 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI WEISSKOPF, MARC G · 2012 to 2013
$476k
Autism Speaks AS1788NCI NIH HHS R01 CA050385NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R21 ES019982NIMH NIH HHS R01 MH078928
6 · The paper itself

Abstract

Maternal posttraumatic stress disorder (PTSD) may be associated with autism spectrum disorder (ASD) in offspring through multiple pathways: maternal stress may affect the fetus; ASD in children may increase risk of PTSD in mothers; and the two disorders may share genetic risk. Understanding whether maternal PTSD is associated with child's ASD is important for clinicians treating children with ASD, as PTSD in parents is associated with poorer family functioning. We examined the association of maternal PTSD with offspring ASD in a large US cohort (N ASD cases = 413, N controls = 42,868). Mother's PTSD symptoms were strongly associated with child's ASD (RR 4-5 PTSD symptoms=1.98, 95% CI=1.39, 2.81; RR 6-7 symptoms=2.89, 95% CI=2.00, 4.18). Clinicians treating persons with ASD should be aware of elevated risk of PTSD in the mother. Genetic studies should investigate PTSD risk alleles in relation to ASD.

Indexed as

Autism spectrum disordergestational effectsposttraumatic stress disorder

Identifiers

PMID24855487
PMCPMC4025916
OpenAlexW1984807202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.