Evidence map›Paper›PMID 24855398›Full record

ArticleJournal of blood medicine2014

Erythropoiesis-stimulating agents for the treatment of chemotherapy-induced anemia: comparisons from real-world clinical experience.

Analia Rodriguez Garzotto, Susana Cortijo Casacajares, Cristina Pernaut, Gustavo Javier Ruiz Ares, Irene Otero Blas, Oliver Heine, Matthew Turner, Francisco Rebollo Laserna, Hernan Cortes Funes, Andreas Lorenz

Erratum issuedAbstract read
In one paragraph

Article in Journal of blood medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Development and 10-year history of a biosimilar: the example of BinocritTherapeutic advances in medical oncology · 2018
    Review
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

  • Erratum issued
    Cortijo Casacajares, Susana [added]; Pernaut, Cristina [added]; Ruiz Ares, Gustavo Javier [added]; Otero Blas, Irene [added]; Cortes Funes, Hernan [added]
5 · Who and what money

Authors and funding

10 authors.

Analia Rodriguez GarzottoHospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
Susana Cortijo CasacajaresHospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
Cristina PernautHospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
Gustavo Javier Ruiz AresHospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
Irene Otero Blas1Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
Oliver HeineZentralklinikum Suhl, Suhl, Germany.
Matthew TurnerSandoz International GmbH, Holzkirchen, Germany.
Francisco Rebollo LasernaSandoz Farmaceutica SA, Madrid, Spain.
Hernan Cortes FunesHospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain.
Andreas LorenzFrauenarztpraxis, Hildburghausen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this paper is to report real-world data on the relative effectiveness of a biosimilar erythropoiesis-stimulating agent (ESA; Binocrit(®)), and other available ESAs for the treatment of chemotherapy-induced anemia.

methodsData were collected retrospectively from single centers in Spain (n=284) and Germany (n=145). Hemoglobin outcomes, transfusion requirements, and serious drug-related adverse events were assessed for each ESA.

resultsHemoglobin outcomes and transfusion requirements were generally similar in the different ESA treatment groups assessed. No serious drug-related adverse events were recorded in any of the treatment groups.

conclusionThese data confirm the real-world effectiveness and safety of a biosimilar ESA (Binocrit(®)) for the treatment of cancer patients with chemotherapy-induced anemia.

Indexed as

biosimilarchemotherapy-induced anemiaerythropoiesis-stimulating agents

Identifiers

PMID24855398
PMCPMC4011805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.