ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2014
Effects of body mass index-related disorders on cognition: preliminary results.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Correlations Between Endocrine Hormones and Cognitive Function in Patients with Obesity: a Cross-sectional Study.Obesity surgery · 2022Article
- Central Obesity, Cardiometabolic Risk, and Cognitive Change in the Study of Latinos - Investigation of Neurocognitive Aging.Journal of Alzheimer's disease : JAD · 2021Article
- Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology.Diabetologia · 2020Article
- The impact of cardiovascular risk factors on cognition in Hispanics and non-Hispanic whites.Learning & memory (Cold Spring Harbor, N.Y.) · 2019Article
- Different risk factors for cognitive impairment among community-dwelling elderly, with impaired fasting glucose or diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Adult Body Height Is a Good Predictor of Different Dimensions of Cognitive Function in Aged Individuals: A Cross-Sectional Study.Frontiers in aging neuroscience · 2016Article
- Using the health action process approach to predict and improve health outcomes in individuals with type 2 diabetes mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2014Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWell-known risk factors for cognitive impairment are also associated with obesity. Research has highlighted genetic risk factors for obesity, yet the relationship of those risk factors with cognitive impairment is unknown. The objective of this study was to determine the associations between cognition, hypertension, diabetes, sleep-disordered breathing, and obesity. Genetic risk factors of obesity were also examined.
methodsThe sample consisted of 369 nondemented individuals aged 50 years or older from four community cohorts. Primary outcome measures included auditory verbal memory, as measured by the Rey Auditory Verbal Learning Test, and executive functioning, as measured by the Color-Word Interference Test of the Delis-Kaplan Executive Function System battery. Apnea-hypopnea index indicators were determined during standard overnight polysomnography. Statistical analyses included Pearson correlations and linear regressions.
resultsPoor executive function and auditory verbal memory were linked to cardiovascular risk factors, but not directly to obesity. Genetic factors appeared to have a small but measureable association to obesity.
conclusionA direct linkage between obesity and poor executive function and auditory verbal memory is difficult to discern, possibly because nonobese individuals may show cognitive impairment due to insulin resistance and the "metabolic syndrome".
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.