Evidence map›Paper›PMID 24855010›Full record

ReviewCancer journal (Sudbury, Mass.)

Gastric microbiome and gastric cancer.

Kyle M Brawner, Casey D Morrow, Phillip D Smith

Open access · greenAbstract readReview
In one paragraph

Review in Cancer journal (Sudbury, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 117 citations in OpenAlex.

  1. Novel anti-virulence strategy againstFrontiers in microbiology · 2026
    Article
  2. Article
  3. Review
  4. A critical review onFrontiers in cellular and infection microbiology · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Volatilomes of human infection.Analytical and bioanalytical chemistry · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Propionibacterium acnes overabundance in gastric cancer promote M2 polarization of macrophages via a TLR4/PI3K/Akt signaling.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Article
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kyle M BrawnerFrom the Departments of *Medicine, †Microbiology, and ‡Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL; and §VA Medical Center Research Service, Birmingham, AL.
Casey D Morrow
Phillip D Smith
Czech Academy of Sciences, Institute of Microbiology · CZUniversity of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Renee A. Heffron · 1988 to 2026
$84.1M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
UAB Skin Diseases Research CenterP30AR050948 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ELMETS, CRAIG A · 2004 to 2013
$5.5M
Mucosal HIV and Immunobiology CenterR24DK064400 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SMITH, PHILLIP D · 2003 to 2012
$4.8M
BASIC MECHANISMS IN AIDS PATHOGENESIST32AI007493 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MORROW, CASEY D · 1995 to 2014
$4.2M
Immunologic Uniqueness of the Female Genital Tract in HIV PathogenesisP01AI083027 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MESTECKY, JIRI F · 2009 to 2010
$4.0M
EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT: PHYSIOLOGYC06RR020136 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MARCHASE, RICHARD BANFIELD · 2004 to 2004
$3.6M
IMMUNOBIOLOGY AND PREVENTION OF H PYLORI DISEASER01DK054495 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SMITH, PHILLIP D · 1998 to 2009
$2.4M
Gastrointestinal Cytomegalovirus Disease: Host and Viral DeterminantsI01CX000372 · VA · BIRMINGHAM VA MEDICAL CENTER · PI SMITH, PHILLIP D · 2011 to 2014
–
CSRD VA I01 CX000372NCATS NIH HHS UL1TR000165NCI NIH HHS P30 CA013148NCRR NIH HHS C06 RR020136NCRR NIH HHS RR-20136NIAID NIH HHS 5P30AI027767NIAID NIH HHS AI083127NIAID NIH HHS P01 AI083027NIAID NIH HHS P30 AI027767NIAID NIH HHS T32 AI007493NIAID NIH HHS T32-AI007493NIAMS NIH HHS P30 AR050948NIAMS NIH HHS P30AR050948NIDDK NIH HHS DK064400NIDDK NIH HHS R01 DK054495NIDDK NIH HHS R24 DK064400
6 · The paper itself

Abstract

Cancer of the stomach is the fourth most common cancer worldwide. The single strongest risk factor for gastric cancer is Helicobacter pylori-associated chronic gastric inflammation. Among persons with H. pylori infection, strain-specific components, host immune responses, and environmental factors influence the risk for gastric disease, including adenocarcinoma of the stomach, although only a small proportion of infected persons develop the malignancy. Recent advances in DNA sequencing technology have uncovered a complex community of noncultivatable inhabitants of the human stomach. The interaction between these inhabitants, collectively referred to as the gastric microbiota, and H. pylori likely affects gastric immunobiology and possibly the sequelae of H. pylori infection. Thus, characterization of the gastric microbiota in subjects with and without H. pylori infection could provide new insight into gastric homeostasis and the pathogenesis of H. pylori-associated disease, including gastric cancer.

Indexed as

AnimalsHelicobacter InfectionsHelicobacter pyloriHumansMicrobiotaRisk FactorsStomach Neoplasms

Identifiers

PMID24855010
PMCPMC4149312
OpenAlexW2331074907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.