Evidence map›Paper›PMID 24855006›Full record

ReviewCancer journal (Sudbury, Mass.)

Intestinal microbiome and lymphoma development.

Mitsuko L Yamamoto, Robert H Schiestl

Open access · greenAbstract readReview
In one paragraph

Review in Cancer journal (Sudbury, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
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  8. Review
  9. Review
  10. Review
  11. Emerging Roles for the Gut Microbiome in Lymphoid Neoplasms.Clinical Medicine Insights. Oncology · 2021
    Review
  12. The Microbiome as a Component of the Tumor Microenvironment.Advances in experimental medicine and biology · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Heavy Chain Disease of the Small Bowel.Current gastroenterology reports · 2018
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mitsuko L YamamotoFrom the Department of Pathology, Environmental Health, Radiation Oncology, UCLA Schools of Medicine and Public Health, Los Angeles, CA.
Robert H Schiestl
Pfizer (United States) · US

Funding

Mechanisms of Intestinal Inflammation - Associated Systemic GenotoxicityR56AI094756 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BRAUN, JONATHAN, SCHIESTL, ROBERT H · 2012 to 2012
$378k
NIAID NIH HHS R56 AI094756
6 · The paper itself

Abstract

The intestinal microbiota and gut immune system must communicate to maintain a balance between tolerance and activation. Our immune system protects us from pathogenic microbes at the same time that our bodies are host to trillions of microbes, symbionts, mutualists, and some that are essential to human health. Since there is such a close interaction between the immune system and the intestinal microbiota, it is not surprising that some lymphomas such as mucosal-associated lymphoid tissue lymphoma have been shown to be caused by the presence of certain bacteria. Animal models have played an important role in elucidating the causation and establishing the mechanism of bacteria-induced mucosal-associated lymphoid tissue lymphoma. In this review, we discuss different ways that animal models have been applied to investigate links between the gut microbiota and lymphoma and have helped to reveal the mechanisms of microbiota-induced lymphoma. Although there is a paucity of published studies demonstrating the interplay between the microbiota and lymphoma development, we believe that the connection is real and that it can be exploited in the future to enhance our understanding of causation and to improve the prognosis and treatment of lymphoma.

Indexed as

MicrobiotaAnimalsDisease Models, AnimalHumansIntestinesLymphoma

Identifiers

PMID24855006
PMCPMC4047521
OpenAlexW2030402706

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.