Evidence map›Paper›PMID 24854175›Full record

ReviewPathogens and global health2014

Parasite virulence, co-infections and cytokine balance in malaria.

Raquel Müller Gonçalves, Nathália Ferreira Lima, Marcelo Urbano Ferreira

Open access · greenAbstract readReview
In one paragraph

Review in Pathogens and global health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Malaria Pathogenesis.Cold Spring Harbor perspectives in medicine · 2018
    Review
  12. Rapid loss of group 1 innate lymphoid cells during blood stageClinical & translational immunology · 2018
    Article
  13. Review
  14. Clinical case reports · 2017
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Raquel Müller Gonçalves
Nathália Ferreira Lima
Marcelo Urbano Ferreira
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strong early inflammatory responses followed by a timely production of regulatory cytokines are required to control malaria parasite multiplication without inducing major host pathology. Here, we briefly examine the homeostasis of inflammatory responses to malaria parasite species with varying virulence levels and discuss how co-infections with bacteria, viruses, and helminths can modulate inflammation, either aggravating or alleviating malaria-related morbidity.

Indexed as

AnimalsCoinfectionCytokinesHomeostasisHost-Parasite InteractionsHumansInflammationLymphocyte ActivationMalariaPlasmodium falciparumPlasmodium vivaxSpecies SpecificityT-Lymphocytes, RegulatoryVirulenceCytokinesCytokines,Immunity,InflammationMalaria,

Identifiers

PMID24854175
PMCPMC4069333
OpenAlexW2033340790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.