ArticleAnnals of botany2014
MADS goes genomic in conifers: towards determining the ancestral set of MADS-box genes in seed plants.
Article in Annals of botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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55 citing papers in PubMed, 160 citations in OpenAlex.
- The other giant: functional significance and divergence of Type I MADS-box genes in the evolution of land plants.Journal of experimental botany · 2026Review
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- Sexual reproduction in land plants: an evolutionary perspective.Plant reproduction · 2025Review
- Genome-wide characterization and expression profiling of MADS-box family genes during organ development and drought stress in Camelina sativa L.Scientific reports · 2025Article
- The dynamic regulatory network of stamens and pistils in papaya.BMC plant biology · 2025Article
- Insights into genetics of floral development in Amborella trichopoda Baill. through genome-wide survey and expression analysis of MADS-Box transcription factors.Scientific reports · 2025Article
- Reflections on the ABC model of flower development.The Plant cell · 2024Review
- Dynamic evolution of MADS-box genes in extant ferns via large-scale phylogenomic analysis.Frontiers in plant science · 2024Article
- Evolutionary Dynamics ofPlants (Basel, Switzerland) · 2023Article
- Genome-Wide Identified MADS-Box Genes inPlants (Basel, Switzerland) · 2023Article
- Updated Phylogeny and Protein Structure Predictions Revise the Hypothesis on the Origin of MADS-box Transcription Factors in Land Plants.Molecular biology and evolution · 2023Article
- Genome-wide analysis of the MADS-box gene family in Lonicera japonica and a proposed floral organ identity model.BMC genomics · 2023Article
- Cracking the Floral Quartet Code: How Do Multimers of MIKCInternational journal of molecular sciences · 2023Review
- A 3D-printed analytical device seamlessly integrating sample treatment for electrochemical detection of IAA in Marchantia polymorpha.Analytical and bioanalytical chemistry · 2023Article
- A long-read and short-read transcriptomics approach provides the first high-quality reference transcriptome and genome annotation for Pseudotsuga menziesii (Douglas-fir).G3 (Bethesda, Md.) · 2023Article
- Genome-Wide Identification of MADS-Box Family Genes in Safflower (International journal of molecular sciences · 2023Article
- Phylogenomic analysis provides insights intoFrontiers in plant science · 2023Article
- The ABC of Flower Development in Monocots: The Model of Rice Spikelet.Methods in molecular biology (Clifton, N.J.) · 2023Article
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3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsMADS-box genes comprise a gene family coding for transcription factors. This gene family expanded greatly during land plant evolution such that the number of MADS-box genes ranges from one or two in green algae to around 100 in angiosperms. Given the crucial functions of MADS-box genes for nearly all aspects of plant development, the expansion of this gene family probably contributed to the increasing complexity of plants. However, the expansion of MADS-box genes during one important step of land plant evolution, namely the origin of seed plants, remains poorly understood due to the previous lack of whole-genome data for gymnosperms.
methodsThe newly available genome sequences of Picea abies, Picea glauca and Pinus taeda were used to identify the complete set of MADS-box genes in these conifers. In addition, MADS-box genes were identified in the growing number of transcriptomes available for gymnosperms. With these datasets, phylogenies were constructed to determine the ancestral set of MADS-box genes of seed plants and to infer the ancestral functions of these genes. KEY
resultsType I MADS-box genes are under-represented in gymnosperms and only a minimum of two Type I MADS-box genes have been present in the most recent common ancestor (MRCA) of seed plants. In contrast, a large number of Type II MADS-box genes were found in gymnosperms. The MRCA of extant seed plants probably possessed at least 11-14 Type II MADS-box genes. In gymnosperms two duplications of Type II MADS-box genes were found, such that the MRCA of extant gymnosperms had at least 14-16 Type II MADS-box genes.
conclusionsThe implied ancestral set of MADS-box genes for seed plants shows simplicity for Type I MADS-box genes and remarkable complexity for Type II MADS-box genes in terms of phylogeny and putative functions. The analysis of transcriptome data reveals that gymnosperm MADS-box genes are expressed in a great variety of tissues, indicating diverse roles of MADS-box genes for the development of gymnosperms. This study is the first that provides a comprehensive overview of MADS-box genes in conifers and thus will provide a framework for future work on MADS-box genes in seed plants.
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