Evidence map›Paper›PMID 24853855›Full record

ArticleSurgical endoscopy2014

Risk factors for anastomotic leakage after laparoscopic low anterior resection with DST anastomosis.

Kenji Kawada, Suguru Hasegawa, Koya Hida, Kenjiro Hirai, Kae Okoshi, Akinari Nomura, Junichiro Kawamura, Satoshi Nagayama, Yoshiharu Sakai

Erratum issued Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04553250 (Randomized Controlled Clinical Trial on Lateral Invagination of the Colorectal Anastomosis by Double Stapling), which is not on this map. Cited by 106 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 10 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04553250 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Randomized Controlled Clinical Trial on Lateral Invagination of the Colorectal Anastomosis by Double Stapling

TypeinterventionalSponsorHospital Clinic of BarcelonaRan2021 to 2023Enrolled786ConditionsAnastomotic Leak, Sigmoid DiseasesArmsDoubled-stapled colorectal anastomosis
3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 10 syntheses or guidelines pooled it, 218 citations in OpenAlex.

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  11. The ILEOSTIM trial: A multicentre randomised controlled trial evaluating the impact of efferent loop stimulation prior to ileostomy reversal on postoperative ileus.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Kenji KawadaDepartment of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawara-cho, Sakyo-ku, Kyoto, 606-8507, Japan, kkawada@kuhp.kyoto-u.ac.jp.
Suguru Hasegawa
Koya Hida
Kenjiro Hirai
Kae Okoshi
Akinari Nomura
Junichiro Kawamura
Satoshi Nagayama
Yoshiharu Sakai
Kyoto University · JPBaptist Memorial Hospital · USJapanese Foundation For Cancer Research · JPSaga University · JPShiga Medical Center for Adults · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic rectal surgery involving rectal transection and anastomosis with stapling devices is technically difficult. The aim of this study was to evaluate the risk factors for anastomotic leakage (AL) after laparoscopic low anterior resection (LAR) with double-stapling technique (DST) anastomosis.

methodsThis was a retrospective single-institution study of 154 rectal cancer patients who underwent laparoscopic LAR with DST anastomosis between June 2005 and August 2013. Patient-, tumor-, and surgery-related variables were examined by univariate and multivariate analyses. The outcome of interest was clinical AL.

resultsThe overall AL rate was 12.3% (19/154). In univariate analysis, tumor size (P = 0.001), operative time (P = 0.049), intraoperative bleeding (P = 0.037), lateral lymph node dissection (P = 0.009), multiple firings of the linear stapler (P = 0.041), and precompression before stapler firings (P = 0.008) were significantly associated with AL. Multivariate analysis identified tumor size (odds ratio [OR] 4.01; 95% confidence interval [CI] 1.25-12.89; P = 0.02) and precompression before stapler firings (OR 4.58; CI 1.22-17.20; P = 0.024) as independent risk factors for AL. In particular, precompression before stapler firing tended to reduce the AL occurring in early postoperative period.

conclusionsUsing appropriate techniques, laparoscopic LAR with DST anastomosis can be performed safely without increasing the risk of AL. Important risk factors for AL were tumor size and precompression before stapler firings.

Indexed as

AdultAgedAged, 80 and overAnastomosis, SurgicalAnastomotic LeakFemaleHumansLaparoscopyLymph Node ExcisionMaleMiddle AgedMultivariate AnalysisOdds RatioOperative TimeRectal NeoplasmsRectum

Identifiers

PMID24853855
PMCPMC4186976
OpenAlexW1996975400

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.