SynthesisJournal of acquired immune deficiency syndromes (1999)2014
Reliability and validity of depression assessment among persons with HIV in sub-Saharan Africa: systematic review and meta-analysis.
Synthesis in Journal of acquired immune deficiency syndromes (1999), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 8 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- The Global Landscape of the Burden of Depressive Symptoms/Major Depression in Individuals Living With HIV/AIDs and Its Effect on Antiretroviral Medication Adherence: An Umbrella Review.Frontiers in psychiatry · 2022Pooled it
- Systematic review and meta-analysis of depression, anxiety, and suicidal ideation among Ph.D. students.Scientific reports · 2021Pooled it
- Burden of Depression in Outpatient HIV-Infected adults in Sub-Saharan Africa; Systematic Review and Meta-analysis.AIDS and behavior · 2020Pooled it
- Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: a systematic review and meta-analysis.AIDS (London, England) · 2018Pooled it
- Pooled it
- The quality of systematic reviews of health-related outcome measurement instruments.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Pooled it
- Syndemics of psychosocial problems and HIV risk: A systematic review of empirical tests of the disease interaction concept.Social science & medicine (1982) · 2015Pooled it
- Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: a systematic review and meta-analysis.Current HIV/AIDS reports · 2014Pooled it
- A randomised equivalence study of the EQ-5D-5L Shona versions: evaluation of measurement equivalence between digital and paper formats.Health and quality of life outcomes · 2026Trial
- Addressing depression, stress, and hopelessness through an economic and relationship-strengthening intervention: Findings from a pilot randomized controlled trial among people with HIV in Malawi.Journal of affective disorders · 2026Trial
- Association of Exposure to Intimate Partner Violence With Maternal Depressive Symptoms and Early Childhood Socioemotional Development Among Mothers and Children in Rural Tanzania.JAMA network open · 2022Trial
- Trial
- Mechanisms and perceived mental health changes after a livelihood intervention for HIV-positive Kenyans: Longitudinal, qualitative findings.Transcultural psychiatry · 2020Trial
- Trial
- The effect of antidepressant treatment on HIV and depression outcomes: results from a randomized trial.AIDS (London, England) · 2015Trial
- Adverse childhood experiences, intimate partner violence, and postpartum depressive symptoms in a pregnancy cohort in Central Vietnam.SSM. Mental health · 2026Article
- Promoting physical function in older adults via physical exercise from a health empowerment perspective: a chain mediation model of social participation and depression.BMC public health · 2026Article
- A psychometric assessment of the factor structure and reliability of the Center for Epidemiological Studies Depression (CES-D) questionnaire in four African nations.BMC psychiatry · 2026Article
- Prevalence and risk factors of hypertension and diabetes among persons living with HIV in Zambia: results of a national facility-based cross-sectional survey.Journal of the International AIDS Society · 2025Article
- Correlates of Sleep Health among Older-Age People with and without HIV in Uganda.AIDS and behavior · 2024Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
objectiveThe aim of this study was to systematically review the reliability and validity of instruments used to screen for major depressive disorder or assess depression symptom severity among persons with HIV in sub-Saharan Africa.
designSystematic review and meta-analysis.
methodsA systematic evidence search protocol was applied to 7 bibliographic databases. Studies examining the reliability and/or validity of depression assessment tools were selected for inclusion if they were based on the data collected from HIV-positive adults in any African member state of the United Nations. A random-effects meta-analysis was used to calculate pooled estimates of depression prevalence. In a subgroup of studies of criterion-related validity, the bivariate random-effects model was used to calculate pooled estimates of sensitivity and specificity.
resultsOf 1117 records initially identified, I included 13 studies of 5373 persons with HIV in 7 sub-Saharan African countries. Reported estimates of Cronbach alpha ranged from 0.63 to 0.95, and analyses of internal structure generally confirmed the existence of a depression-like construct accounting for a substantial portion of variance. The pooled prevalence of probable depression was 29.5% [95% confidence interval (CI): 20.5 to 39.4], whereas the pooled prevalence of major depressive disorder was 13.9% (95% CI: 9.7 to 18.6). The Center for Epidemiologic Studies Depression scale was the most frequently studied instrument, with a pooled sensitivity of 0.82 (95% CI: 0.73 to 0.87) for detecting major depressive disorder.
conclusionsDepression-screening instruments yielded relatively high false positive rates. Overall, few studies described the reliability and/or validity of depression instruments in sub-Saharan Africa.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.