Evidence map›Paper›PMID 24853292›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2014

Exercise-induced pulse wave velocity changes in untreated patients with essential hypertension: the effect of an angiotensin receptor antagonist.

Eugenia Gkaliagkousi, Eleni Gavriilaki, Barbara Nikolaidou, George Triantafyllou, Stella Douma

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Renin-angiotensin system blockade and exercise-induced increase in aortic stiffness.Journal of clinical hypertension (Greenwich, Conn.) · 2014
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Eugenia Gkaliagkousi2nd Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Eleni Gavriilaki
Barbara Nikolaidou
George Triantafyllou
Stella Douma

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates arterial stiffness changes after acute exercise in young patients with untreated, recently diagnosed grade I essential hypertension (UH) compared with normotensive (NT) individuals and the effect of antihypertensive treatment on this phenomenon. Study 1 consisted of 25 UH and 15 NT patients. UH patients who received treatment were included in study 2 and were followed-up after a 3-month treatment period with an angiotensin II receptor blocker. Aortic pulse wave velocity (PWV) was assessed at baseline, at maximal exercise, and at 10, 30, and 60 minutes later. In UH patients, PWV increased significantly at maximal exercise and 10 and 30 minutes of recovery, despite blood pressure fall to baseline levels. No significant PWV changes were observed in NT patients. Post-treatment PWV levels were significantly decreased and similar to those of NT patients. Arterial stiffness is impaired following high-intensity acute exercise even in the early stages of hypertension. Antihypertensive treatment ameliorates these effects.

Indexed as

AdultAngiotensin II Type 1 Receptor BlockersAntihypertensive AgentsArteriesBlood PressureBlood Pressure DeterminationElectrocardiographyEssential HypertensionExerciseFemaleHumansHypertensionMaleMiddle AgedPulse Wave AnalysisTetrazolesAngiotensin II Type 1 Receptor BlockersAntihypertensive AgentsTetrazolesValineValsartan

Identifiers

PMID24853292
PMCPMC8031989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.