Evidence map›Paper›PMID 24853131›Full record

ArticleInternational journal of molecular sciences2014

Effect of a novel quaternary ammonium methacrylate polymer (QAMP) on adhesion and antibacterial properties of dental adhesives.

Yasmine M Pupo, Paulo Vitor Farago, Jessica M Nadal, Luzia C Simão, Luís Antônio Esmerino, Osnara M M Gomes, João Carlos Gomes

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yasmine M PupoPostgraduate Program in Dentistry, Department of Dentistry, State University of Ponta Grossa, Paraná 84030-900, Brazil. yasminemendes@hotmail.com.
Paulo Vitor FaragoLaboratory of Pharmaceutical Products, Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, State University of Ponta Grossa, Paraná 84030-900, Brazil. pvfarago@uepg.br.
Jessica M NadalLaboratory of Pharmaceutical Products, Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, State University of Ponta Grossa, Paraná 84030-900, Brazil. jessicabem@hotmail.com.
Luzia C SimãoMulti-user Laboratory, State University of Ponta Grossa, Paraná 84030-900, Brazil. luziachaves4@hotmail.com.
Luís Antônio EsmerinoLaboratory of Clinical Microbiology, Department of Clinical and Toxicological Analysis, State University of Ponta Grossa, Paraná, 84030-900, Brazil. esmerino@uepg.br.
Osnara M M GomesPostgraduate Program in Dentistry, Department of Dentistry, State University of Ponta Grossa, Paraná 84030-900, Brazil. osnaramgomes@uol.com.br.
João Carlos GomesPostgraduate Program in Dentistry, Department of Dentistry, State University of Ponta Grossa, Paraná 84030-900, Brazil. gomesjoaocarlos@uol.com.br.
Universidade Estadual de Ponta Grossa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the resin-dentin bond strength (μTBS), degree of conversion (DC), and antibacterial potential of an innovative adhesive system containing a quaternary ammonium methacrylate polymer (QAMP) using in situ and in vitro assays. Forty-two human third molars were flattened until the dentin was exposed and were randomly distributed into three groups of self-etching adhesive systems: Clearfil™ SE Bond containing 5% QAMP (experimental group), Clearfil™ Protect Bond (positive control) and Clearfil™ SE Bond (negative control). After light curing, three 1 mm-increments of composite resin were bonded to each dentin surface. A total of thirty of these bonded teeth (10 teeth per group) was sectioned to obtain stick-shaped specimens and tested under tensile stress immediately, and after 6 and 12 months of storage in distilled water. Twelve bonded teeth (4 teeth per group) were longitudinally sectioned in a mesio-to-distal direction to obtain resin-bonded dentin slabs. In situ DC was evaluated by micro-Raman spectroscopy. In vitro DC of thin films of each adhesive system was measured using Fourier transform infrared spectroscopy. In vitro susceptibility tests of these three adhesive systems were performed by the minimum inhibitory/minimum bactericidal concentration (MIC/MBC) assays against Streptococcus mutans, Lactobacillus casei, and Actinomyces naeslundii. No statistically significant difference in μTBS was observed between Clearfil™ SE Bond containing 5% QAMP and Clearfil™ SE Bond (p>0.05) immediately, and after 6 and 12 months of water storage. However Clearfil™ Protect Bond showed a significant reduction of μTBS after 12 months of storage (p=0.039). In addition, QAMP provided no significant change in DC after incorporating into Clearfil™ SE Bond (p>0.05). Clearfil™ SE Bond containing 5% QAMP demonstrated MIC/MBC values similar to the positive control against L. casei and A. naeslundii and higher than the negative control for all evaluated bacterial strains. The use of QAMP in an adhesive system demonstrated effective bond strength, a suitable degree of conversion, and adequate antibacterial effects against oral bacteria, and may be useful as a new approach to provide long-lasting results for dental adhesives.

Indexed as

ActinomycesComposite ResinsCuring Lights, DentalDental BondingDental CementsHumansLacticaseibacillus caseiMaterials TestingMethacrylatesMicrobial Sensitivity TestsPolymersQuaternary Ammonium CompoundsStreptococcus mutansSurface PropertiesTensile StrengthTime FactorsComposite ResinsDental CementsMethacrylatesPolymersQuaternary Ammonium Compounds

Identifiers

PMID24853131
PMCPMC4057771
OpenAlexW2041741714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.