Evidence map›Paper›PMID 24852251›Full record

ArticleNucleic acids research2014

StemCellNet: an interactive platform for network-oriented investigations in stem cell biology.

José P Pinto, Ravi Kiran Reddy Kalathur, Rui S R Machado, Joana M Xavier, José Bragança, Matthias E Futschik

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Informatics Approaches for Harmonized Intelligent Integration of Stem Cell Research.Stem cells and cloning : advances and applications · 2020
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Web resources for stem cell research.Genomics, proteomics & bioinformatics · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

José P PintoCentre for Molecular and Structural Biomedicine, CBME/IBB, LA, University of Algarve, Faro, Algarve 8005-139, Portugal jppinto@ualg.pt.
Ravi Kiran Reddy KalathurCentre for Molecular and Structural Biomedicine, CBME/IBB, LA, University of Algarve, Faro, Algarve 8005-139, Portugal.
Rui S R MachadoCentre for Molecular and Structural Biomedicine, CBME/IBB, LA, University of Algarve, Faro, Algarve 8005-139, Portugal.
Joana M XavierCentre for Molecular and Structural Biomedicine, CBME/IBB, LA, University of Algarve, Faro, Algarve 8005-139, Portugal.
José BragançaCentre for Molecular and Structural Biomedicine, CBME/IBB, LA, University of Algarve, Faro, Algarve 8005-139, Portugal Department of Biomedical Sciences and Medicine, University of Algarve, Faro, Algarve 8005-139, Portugal.
Matthias E FutschikCentre for Molecular and Structural Biomedicine, CBME/IBB, LA, University of Algarve, Faro, Algarve 8005-139, Portugal Centre of Marine Science, University of Algarve, Faro, Algarve 8005-139, Portugal jppinto@ualg.pt.
University of Algarve · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells are characterized by their potential for self-renewal and their capacity to differentiate into mature cells. These two key features emerge through the interplay of various factors within complex molecular networks. To provide researchers with a dedicated tool to investigate these networks, we have developed StemCellNet, a versatile web server for interactive network analysis and visualization. It rapidly generates focused networks based on a large collection of physical and regulatory interactions identified in human and murine stem cells. The StemCellNet web-interface has various easy-to-use tools for selection and prioritization of network components, as well as for integration of expression data provided by the user. As a unique feature, the networks generated can be screened against a compendium of stemness-associated genes. StemCellNet can also indicate novel candidate genes by evaluating their connectivity patterns. Finally, an optional dataset of generic interactions, which provides large coverage of the human and mouse proteome, extends the versatility of StemCellNet to other biomedical research areas in which stem cells play important roles, such as in degenerative diseases or cancer. The StemCellNet web server is freely accessible at http://stemcellnet.sysbiolab.eu.

Indexed as

Gene Regulatory NetworksSoftwareAnimalsGene ExpressionHumansInternetMiceProtein Interaction MappingProteomeStem CellsProteome

Identifiers

PMID24852251
PMCPMC4086070
OpenAlexW2001903358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.