ArticleJournal of Korean medical science2014
Methylenetetrahydrofolate reductase 677 genotype-specific reference values for plasma homocysteine and serum folate concentrations in korean population aged 45 to 74 years: the Namwon study.
Article in Journal of Korean medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Are vitamin B-12 measurements adequate for evaluating its deficiency in individuals?Asia Pacific journal of clinical nutrition · 2025Article
- Diagnostic Value of Homocysteine Metabolic Pathway in Coronary Atherosclerosis: A Study on Reference Intervals and Risk Prediction.International journal of general medicine · 2025Article
- Retrospective study to identify homocysteine reference intervals in healthy Chinese 60 years of age and above.Journal of medical biochemistry · 2023Article
- Association Between Plasma Homocysteine Level and Mortality: A Mendelian Randomization Study.Korean circulation journal · 2023Article
- Establishment of Reference Interval and Aging Model of Homocysteine Using Real-World Data.Frontiers in cardiovascular medicine · 2022Article
- Sex differences in risk factors for stroke in patients with hypertension and hyperhomocysteinemia.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 percentile]) were 7.72 (5.03 to 13.80) and 6.09 (3.95-10.19) in men and women, respectively. For serum folate concentration (nM/L), reference values were 23.71 (11.73-38.44) and 28.95 (15.23-40.44) in men and women, respectively. The tHcy levels of both genders in the present study were lower than those in previous reports from other countries and Korea.
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Registered trials
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