ArticleMolecular biology and evolution2014
Natural variation in abiotic stress responsive gene expression and local adaptation to climate in Arabidopsis thaliana.
Article in Molecular biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 164 citations in OpenAlex.
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- Evolution of regulatory networks controlling plasticity in gene expression betweenbioRxiv : the preprint server for biology · 2026Article
- Functional genomic map of local adaptation in sorghum to guide allele mining.bioRxiv : the preprint server for biology · 2026Article
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- Accelerated Flowering and Differential Florigen Gene Expression of SeagrassEcology and evolution · 2026Article
- Experimental Validation of Genome-Environment Associations in Arabidopsis.Molecular ecology · 2025Article
- Variation in the Molecular Phenotype of βglu-1, an Insect Defence-Related Beta-Glucosidase Gene, in Two Transcontinental Picea Species.Molecular ecology · 2025Article
- Local adaptation of both plant and pathogen: an arms-race compromise in switchgrass rust.The New phytologist · 2025Article
- Predicting Gene Expression Responses to Cold inGenes · 2025Article
- Climate change and plant genomic plasticity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Trans-regulatory loci shape natural variation of gene expression plasticity in Arabidopsis.Genetics · 2025Article
- Characterizing genetic adaptations and plastic stress responses within a transcontinental North American keystone species.Tree physiology · 2025Article
- Landscape transcriptomics as a tool for addressing global change effects across diverse species.Molecular ecology resources · 2025Review
- Advancing ecological and evolutionary research in Arabidopsis: Extending insights into model and nonmodel plants.The Plant cell · 2025Review
- Neutral transcriptome rewiring promotes quantitative disease resistance evolvability at the species level.The Plant cell · 2025Article
- Enhancers in Plant Development, Adaptation and Evolution.Plant & cell physiology · 2025Review
- It's all in the timing: vegetative phase change alters selection under drought and contributes to local adaptation.bioRxiv : the preprint server for biology · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene expression varies widely in natural populations, yet the proximate and ultimate causes of this variation are poorly known. Understanding how variation in gene expression affects abiotic stress tolerance, fitness, and adaptation is central to the field of evolutionary genetics. We tested the hypothesis that genes with natural genetic variation in their expression responses to abiotic stress are likely to be involved in local adaptation to climate in Arabidopsis thaliana. Specifically, we compared genes with consistent expression responses to environmental stress (expression stress responsive, "eSR") to genes with genetically variable responses to abiotic stress (expression genotype-by-environment interaction, "eGEI"). We found that on average genes that exhibited eGEI in response to drought or cold had greater polymorphism in promoter regions and stronger associations with climate than those of eSR genes or genomic controls. We also found that transcription factor binding sites known to respond to environmental stressors, especially abscisic acid responsive elements, showed significantly higher polymorphism in drought eGEI genes in comparison to eSR genes. By contrast, eSR genes tended to exhibit relatively greater pairwise haplotype sharing, lower promoter diversity, and fewer nonsynonymous polymorphisms, suggesting purifying selection or selective sweeps. Our results indicate that cis-regulatory evolution and genetic variation in stress responsive gene expression may be important mechanisms of local adaptation to climatic selective gradients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.