Evidence map›Paper›PMID 24850345›Full record

ArticleJournal of clinical microbiology2014

Impact of isolated hepatitis C virus (HCV) core-specific antibody detection and viral RNA amplification among HCV-seronegative dialysis patients at risk for infection.

Guillermina Barril, Juan A Quiroga, María Dolores Arenas, Mario Espinosa, Nuria García-Fernández, Secundino Cigarrán, José A Herrero, Gloria del Peso, Pilar Caro, Rebeca García-Agudo and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 1 country.

Guillermina BarrilNephrology, Hospital Universitario de La Princesa, Madrid, Spain.
Juan A QuirogaFundación Estudio Hepatitis Virales, Madrid, Spain.
María Dolores ArenasNephrology, Hospital Perpetuo Socorro, Alicante, Spain.
Mario EspinosaNephrology, Hospital Reina Sofía, Cordoba, Spain.
Nuria García-FernándezNephrology, Clínica Universitaria de Navarra, Pamplona, Spain.
Secundino CigarránNephrology, Hospital da Costa, Burela, Lugo, Spain.
José A HerreroNephrology, Hospital Clínico San Carlos, Madrid, Spain.
Gloria del PesoNephrology, Hospital La Paz, Madrid, Spain.
Pilar CaroNephrology, Clínica Rúber, Madrid, Spain.
Rebeca García-AgudoComplejo Hospitalario La Mancha-Centro, Alcázar de San Juan, Ciudad Real, Spain.
Yésica AmézquitaClínica Fuensanta, Madrid, Spain.
Ana BlancoDial Centro, Madrid, Spain.
Pilar Martínez-RubioICN El Pilar, Madrid, Spain.
José M AlcázarNephrology, Hospital 12 de Octubre, Madrid, Spain.
Emilio González-ParraNephrology, Hospital Central de la Defensa, Madrid, Spain.
Adoración Martín-GómezNephrology, Hospital de Poniente, Almería, Spain.
Inmaculada CastilloFundación Estudio Hepatitis Virales, Madrid, Spain.
Javier BartoloméFundación Estudio Hepatitis Virales, Madrid, Spain.
Vicente CarreñoFundación Estudio Hepatitis Virales, Madrid, Spain fehvhpa@fehv.org.
Fundación para el Estudio de las Hepatitis Virales · ESClínica Rementería · ESClinica Universidad de Navarra · ESHospital Central de la Defensa Gómez Ulla · ESHospital Clínico San Carlos · ESHospital de Poniente · ESHospital Perpetuo Socorro · ESHospital Ruber Internacional · ESHospital Universitario de La Princesa · ESHospital Universitario La Paz · ESHospital Universitario Reina Sofía · ESResearch Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amplification of hepatitis C virus (HCV) RNA from blood detected occult HCV infections in 30.9% of 210 HCV-seronegative dialysis patients with abnormal liver enzyme levels that had evaded standard HCV testing practices. Isolated HCV core-specific antibody detection identified three additional anti-HCV screening-negative patients lacking HCV RNA amplification in blood who were considered potentially infectious. Together, these findings may affect management of the dialysis setting.

Indexed as

AdultAgedAged, 80 and overEnzymesFemaleHepatitis CHepatitis C AntibodiesHumansLiver Function TestsMaleMiddle AgedPeptide FragmentsRenal DialysisRNA, ViralViral Core Proteinscore protein (1-120), hepatitis C virusEnzymesHepatitis C AntibodiesPeptide FragmentsRNA, ViralViral Core Proteins

Identifiers

PMID24850345
PMCPMC4136170
OpenAlexW2134195808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.