Pooling data on different probiotics is not appropriate to assess the efficacy of probiotics.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed, 8 syntheses or guidelines pooled it.

1. The Health Benefits of Probiotic Lactiplantibacillus plantarum: A Systematic Review and Meta-Analysis.Probiotics and antimicrobial proteins · 2025
   Pooled it
2. Probiotics for the prevention of Clostridioides difficile-associated diarrhea in adults and children.The Cochrane database of systematic reviews · 2025
   Pooled it
3. Efficacy of Single-Strain Probiotics Versus Multi-Strain Mixtures: Systematic Review of Strain and Disease Specificity.Digestive diseases and sciences · 2021
   Pooled it
4. Efficacy of Lactobacillus-supplemented triple therapy for H. pylori eradication: A meta-analysis of randomized controlled trials.PloS one · 2019
   Pooled it
5. Efficacy of Lactobacillus-supplemented triple therapy for Helicobacter pylori infection in children: a meta-analysis of randomized controlled trials.European journal of pediatrics · 2019
   Pooled it
6. Probiotics for respiratory tract infections in children attending day care centers-a systematic review.European journal of pediatrics · 2018
   Pooled it
7. Choosing an appropriate probiotic product for your patient: An evidence-based practical guide.PloS one · 2018
   Pooled it
8. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children.The Cochrane database of systematic reviews · 2017
   Pooled it
9. Current paradigms in the management of refractory Helicobacter pylori infection.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
   Review
10. Specific Probiotics for the Treatment of Pediatric Acute Gastroenteritis in India: A Systematic Review and Meta-Analysis.JPGN reports · 2021
    Review
11. Strain-Specificity and Disease-Specificity of Probiotic Efficacy: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2018
    Article
12. Probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disorders.British journal of pharmacology · 2017
    Review
13. Systematic review and meta-analysis: Multi-strain probiotics as adjunct therapy for Helicobacter pylori eradication and prevention of adverse events.United European gastroenterology journal · 2016
    Article

Corrections and comments

• Comment on
  Meta-analysis of randomized controlled trials on the efficacy of probiotics in Helicobacter pylori eradication therapy in children.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as