Evidence map›Paper›PMID 24848495›Full record

ArticleAlcoholism, clinical and experimental research2014

Psychiatric comorbidity and perceived alcohol stigma in a nationally representative sample of individuals with DSM-5 alcohol use disorder.

Joseph E Glass, Emily C Williams, Kathleen K Bucholz

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Joseph E GlassSchool of Social Work, University of Wisconsin-Madison, Madison, Wisconsin.
Emily C Williams
Kathleen K Bucholz
University of Wisconsin–Madison · USVA Puget Sound Health Care System · USWashington University in St. Louis · US

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JESSICA E SALVATORE · 1989 to 2026
$162.7M
Resource CoreP60AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI BARTHOLOW, BRUCE D · 2009 to 2013
$8.8M
Alcoholism: Epidemiologic High Risk Family Study - MOFAMR01AA012640 · NIAAA · WASHINGTON UNIVERSITY · PI BUCHOLZ, KATHLEEN KEENAN · 2001 to 2011
$6.3M
Gene Environment in Outcomes of Offspring of Twins with Substance Use DisordersR01DA014363 · NIDA · WASHINGTON UNIVERSITY · PI BUCHOLZ, KATHLEEN KEENAN · 2001 to 2011
$5.7M
Transdisciplinary Training in Addictions ResearchT32DA015035 · NIDA · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Patricia A Cavazos-Rehg · 2002 to 2026
$5.3M
IMPLEMENTATION RESEARCH INSTITUTE FOR MENTAL HEALTH SERVICES IRI-MHSR25MH080916 · NIMH · WASHINGTON UNIVERSITY · PI Byron James Powell · 2009 to 2026
$3.7M
ALCOHOL DEPENDENCE IN AFRICAN AMERICANS: A CASE-CONTROL GENETIC STUDYR01AA017444 · NIAAA · WASHINGTON UNIVERSITY · PI GRUCZA, RICHARD A · 2009 to 2013
$3.3M
ALCOHOL USE DISORDER IN YOUNG WOMEN: GENETIC EPIDEMIOLOGY: MOAFTS WAVE 7R01AA017915 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2009 to 2013
$3.2M
PHARMACOKINETICS AND PHARMACOLOGICAL EFFECTS OF ALCOHOL AFTER BARIATRIC SURGERYR21AA020018 · NIAAA · WASHINGTON UNIVERSITY · PI PEPINO DE GRUEV, MARTA YANINA · 2012 to 2013
$404k
Perceived alcohol stigma and treatment for alcohol use disordersF31AA021034 · NIAAA · WASHINGTON UNIVERSITY · PI GLASS, JOSEPH EDWIN · 2011 to 2011
$30k
Implementation Research for Evidence-based Care for Alcohol DependenceIK2HX001161 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI WILLIAMS, EMILY CATERINA · 2015 to 2015
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HSRD VA IK2 HX001161NIAAA NIH HHS 1F31AA021034NIAAA NIH HHS F31 AA021034NIAAA NIH HHS P60 AA011998NIAAA NIH HHS P60AA011998NIAAA NIH HHS R01AA012460NIAAA NIH HHS R01 AA012640NIAAA NIH HHS R01 AA017444NIAAA NIH HHS R01AA017444NIAAA NIH HHS R01 AA017915NIAAA NIH HHS R01AA017915NIAAA NIH HHS R21 AA020018NIAAA NIH HHS R21AA020018NIAAA NIH HHS U01AA008401NIAAA NIH HHS U10 AA008401NIDA NIH HHS R01 DA014363NIDA NIH HHS R01DA014363NIDA NIH HHS T32 DA015035NIMH NIH HHS R25 MH080916NIMH NIH HHS R25 MH080916-01A2
6 · The paper itself

Abstract

backgroundAlcohol use disorder (AUD) is among the most stigmatized health conditions and is frequently comorbid with mood, anxiety, and drug use disorders. Theoretical frameworks have conceptualized stigma-related stress as a predictor of psychiatric disorders. We described profiles of psychiatric comorbidity among people with AUD and compared levels of perceived alcohol stigma across profiles.

methodsCross-sectional data were analyzed from a general population sample of U.S. adults with past-year DSM-5 AUD (n = 3,368) from the National Epidemiologic Survey on Alcohol and Related Conditions, which was collected from 2001 to 2005. Empirically derived psychiatric comorbidity profiles were established with latent class analysis, and mean levels of perceived alcohol stigma were compared across the latent classes while adjusting for sociodemographic characteristics and AUD severity.

resultsFour classes of psychiatric comorbidity emerged within this AUD sample, including those with: (i) high comorbidity, reflecting internalizing (i.e., mood and anxiety disorders) and externalizing (i.e., antisocial personality and drug use disorders) disorders; (ii) externalizing comorbidity; (iii) internalizing comorbidity; and (iv) no comorbidity. Perceived alcohol stigma was significantly higher in those with internalizing comorbidity (but not those with high comorbidity) as compared to those with no comorbidity or externalizing comorbidity.

conclusionsPerceived stigma, as manifested by anticipations of social rejection and discrimination, may increase risk of internalizing psychiatric comorbidity. Alternatively, internalizing psychiatric comorbidity could sensitize affected individuals to perceive more negative attitudes toward them. Future research is needed to understand causal and bidirectional associations between alcohol stigma and psychiatric comorbidity.

Indexed as

StereotypingAdultAgedAlcoholismAnxiety DisordersComorbidityFemaleHumansMaleMental DisordersMiddle AgedMood DisordersSubstance-Related DisordersUnited StatesAlcoholAlcoholism StigmaLatent Class AnalysisPerceived StigmaPsychiatric Disorders

Identifiers

PMID24848495
PMCPMC4059348
OpenAlexW2149838552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.