Evidence map›Paper›PMID 24848074›Full record

ReviewMinerva ginecologica2014

Ovarian cancer in endometriosis: clinical and molecular aspects.

B Lyttle, L Bernardi, M E Pavone

Abstract readReview
In one paragraph

Review in Minerva ginecologica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Endometriosis and ovarian cancer: Their association and relationship.European journal of obstetrics & gynecology and reproductive biology: X · 2019
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B LyttleObstetrics and Gynecology University of Massachusetts Medical School Worcester, MA, USA - mpavone@nmff.org.
L Bernardi
M E Pavone
University of Massachusetts Chan Medical School · US

Funding

Project 3: Medically-based Protection of the Ovarian Reserve Against Anti-CancerP50HD076188 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOODRUFF, TERESA K · 2014 to 2017
$6.2M
Project 3: Medically-based Protection of the Ovarian Reserve Against Anti-CancerU54HD076188 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOODRUFF, TERESA K · 2013 to 2013
$1.6M
Ex Vivo Female Reproductive Tract Integration In a 3D Microphysiologic SystemUH2ES022920 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOODRUFF, TERESA K · 2012 to 2013
$1.2M
NICHD NIH HHS P50 HD076188NICHD NIH HHS U54 HD076188NICHD NIH HHS U54HD076188NIEHS NIH HHS UH2 ES022920
6 · The paper itself

Abstract

Endometriosis is a gynecological condition characterized by specific histological, molecular and clinical findings, that affects 5-10% of premenopausal women and has been implicated as a precursor for certain types of ovarian cancer. Clinical studies of endometriosis associated ovarian cancer (EAOC) suggest that patients present at a young age with a lower stage and grade of tumor, and are more likely to be premenopausal than women with other ovarian cancers. However, when overall survival is compared between these types of ovarian cancers, there is no difference noted. In addition, EAOC tumors are more likely to be found with a concurrent diagnosis of cancer, most commonly endometrial. Advances in technology, primarily the ability for whole genome sequencing, have led to the discovery of new mutations and further understanding of previously identified genes and pathways associated with EAOCs including PTEN, CTNNB1 (beta-catenin), KRAS, microsatellite instability and ARID1A. This paper will review the most recent clinical and molecular advances in the association of endometriosis and ovarian cancer.

Indexed as

PremenopauseAge FactorsEndometriosisFemaleHumansMicrosatellite InstabilityMutationNeoplasm GradingNeoplasm StagingOvarian NeoplasmsSurvival Rate

Identifiers

PMID24848074
PMCPMC5312665
OpenAlexW2302834983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.