ArticleMolecular biology reports2014
Differential expression of genes and proteins associated with wool follicle cycling.
Article in Molecular biology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Proteomics Reveals the Role of PLIN2 in Regulating the Secondary Hair Follicle Cycle in Cashmere Goats.International journal of molecular sciences · 2025Article
- Genomic Regions Associated with Wool, Growth and Reproduction Traits in Uruguayan Merino Sheep.Genes · 2023Article
- Expression and distribution of EPHA4 and Ephrin A3 in Aohan fine-wool sheep skin.Archives animal breeding · 2022Article
- Timing of Transcriptomic Peripheral Blood Mononuclear Cell Responses of Sheep toFrontiers in immunology · 2021Article
- Discovery of genes and proteins possibly regulating mean wool fibre diameter using cDNA microarray and proteomic approaches.Scientific reports · 2020Article
- The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits.BMC developmental biology · 2020Article
- Analysis of FK506-mediated functional recovery and neuroprotection in a rat model of spinal cord injury indicates that EGF is modulated in astrocytes.Experimental and therapeutic medicine · 2018Article
- Defining Key Genes Regulating Morphogenesis of Apocrine Sweat Gland in Sheepskin.Frontiers in genetics · 2018Article
- High-resolution analysis of selection sweeps identified between fine-wool Merino and coarse-wool Churra sheep breeds.Genetics, selection, evolution : GSE · 2017Article
- A comparison of transcriptomic patterns measured in the skin of Chinese fine and coarse wool sheep breeds.Scientific reports · 2017Article
- Identification of skin-expressed genes possibly associated with wool growth regulation of Aohan fine wool sheep.BMC genetics · 2014Article
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sheep are valuable resources for the wool industry. Wool growth of Aohan fine wool sheep has cycled during different seasons in 1 year. Therefore, identifying genes that control wool growth cycling might lead to ways for improving the quality and yield of fine wool. In this study, we employed Agilent sheep gene expression microarray and proteomic technology to compare the gene expression patterns of the body side skins at August and December time points in Aohan fine wool sheep (a Chinese indigenous breed). Microarray study revealed that 2,223 transcripts were differentially expressed, including 1,162 up-regulated and 1,061 down-regulated transcripts, comparing body side skin at the August time point to the December one (A/D) in Aohan fine wool sheep. Then seven differentially expressed genes were selected to validated the reliability of the gene chip data. The majority of the genes possibly related to follicle development and wool growth could be assigned into the categories including regulation of receptor binding, extracellular region, protein binding and extracellular space. Proteomic study revealed that 84 protein spots showed significant differences in expression levels. Of the 84, 63 protein spots were upregulated and 21 were downregulated in A/D. Finally, 55 protein points were determined through MALDI-TOF/MS analyses. Furthermore, the regulation mechanism of hair follicle might resemble that of fetation.
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