ArticleFrontiers in public health2014
Antidepressants: relationship to the time to psychiatric readmission and probability of being in hospital in depressive patients.
Article in Frontiers in public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Comparison of the Effectiveness of Different Antidepressants in Preventing Psychiatric Rehospitalization.Cureus · 2024Article
- Readmission rates and predictors of avoidable readmissions in older adults in a tertiary care centre.Journal of family medicine and primary care · 2022Article
- The economic burden of inpatient care of depression in Poznan (Poland) and Kiel (Germany) in 2016.PloS one · 2018Article
- FAM-FACE-SG: a score for risk stratification of frequent hospital admitters.BMC medical informatics and decision making · 2017Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough antidepressants play a major role in the treatment of patients with depression, it is unclear which specific antidepressants are more efficacious than others. This study aims to analyze the relationship between several antidepressant substances and the time to readmission as well as the probability of being in hospital in a given week by using prescription data.
methodsThe database was health-insurance claim data from the new Federal States in Germany. The analysis consisted of all patients with unipolar depression at their index admission in 2007 (N = 1803). Patients were followed up for 2 years after discharge from index hospitalization. Statistical analyses were conducted by discrete-time hazards models and general estimation equation models, accounting for various predictors.
resultsOf all prescribed antidepressant substances, sertraline was related to an increased time to readmission by 37% and to a reduction in the probability of being in hospital in a given week by 40%. However, it was prescribed to only about 5% of the patients.
conclusionIn this study, only sertraline appeared to have clinical and economic advantages. It is remarkable that just a minority of patients received sertraline in our study, thus differing from the prescription pattern in the US.
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