Evidence map›Paper›PMID 24847214›Full record

ReviewFrontiers in neuroanatomy2014

Spatiotemporal dynamics of dendritic spines in the living brain.

Chia-Chien Chen, Ju Lu, Yi Zuo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroanatomy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Unraveling the mysteries of dendritic spine dynamics: Five key principles shaping memory and cognition.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2023
    Article
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  5. Aberrant cortical spine dynamics after concussive injury are reversed by integrated stress response inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2022
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  11. Review
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  14. The Subcortical-Allocortical- NeocorticalFrontiers in synaptic neuroscience · 2021
    Article
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  17. Review
  18. Article
  19. Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  20. Estrogen-Dependent Functional Spine Dynamics in Neocortical Pyramidal Neurons of the Mouse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chia-Chien ChenDepartment of Molecular, Cell and Developmental Biology, University of California at Santa Cruz Santa Cruz, CA, USA.
Ju LuDepartment of Biological Sciences and James H. Clark Center, Stanford University Stanford, CA, USA.
Yi ZuoDepartment of Molecular, Cell and Developmental Biology, University of California at Santa Cruz Santa Cruz, CA, USA.
Clark University · US

Funding

Development of synaptic abnormality in fragile X miceR01MH094449 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2012 to 2015
$1.5M
NIMH NIH HHS R01 MH094449
6 · The paper itself

Abstract

Dendritic spines are ubiquitous postsynaptic sites of most excitatory synapses in the mammalian brain, and thus may serve as structural indicators of functional synapses. Recent works have suggested that neuronal coding of memories may be associated with rapid alterations in spine formation and elimination. Technological advances have enabled researchers to study spine dynamics in vivo during development as well as under various physiological and pathological conditions. We believe that better understanding of the spatiotemporal patterns of spine dynamics will help elucidate the principles of experience-dependent circuit modification and information processing in the living brain.

Indexed as

cerebral cortexdendritic spineexperience-dependent plasticityin vivoneural circuittwo-photon imaging

Identifiers

PMID24847214
PMCPMC4023020
OpenAlexW2141331098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.