Evidence map›Paper›PMID 24847001›Full record

ArticleMicrobiology (Reading, England)2014

Neurospora crassa 1,3-α-glucan synthase, AGS-1, is required for cell wall biosynthesis during macroconidia development.

Ci Fu, Asuma Tanaka, Stephen J Free

Open access · greenAbstract read
In one paragraph

Article in Microbiology (Reading, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Characterization of the Polysaccharide and Protein Composition ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Optimization of Protoplast Preparation Conditions inJournal of fungi (Basel, Switzerland) · 2024
    Article
  3. Structural diversification of fungal cell wall in response to the stress signaling and remodeling during fungal pathogenesis.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024
    Review
  4. Characterization ofCell surface (Amsterdam, Netherlands) · 2022
    Article
  5. Article
  6. Off the wall: The rhyme and reason ofCell surface (Amsterdam, Netherlands) · 2019
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Hyphal ontogeny inF1000Research · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ci FuDepartment of Biological Sciences, SUNY University at Buffalo, Buffalo, NY 14260, USA.
Asuma TanakaDepartment of Biological Sciences, SUNY University at Buffalo, Buffalo, NY 14260, USA.
Stephen J FreeDepartment of Biological Sciences, SUNY University at Buffalo, Buffalo, NY 14260, USA.
University at Buffalo, State University of New York · US

Funding

Tools for Functional Analysis and Cell BiologyP01GM068087 · NIGMS · DARTMOUTH COLLEGE · PI DUNLAP, JAY C. · 2004 to 2013
$19.3M
Characterization of Neurospora cell fusion eventsR01GM078589 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI FREE, STEPHEN J. · 2006 to 2010
$830k
NIGMS NIH HHS P01 GM068087NIGMS NIH HHS R01 GM078589
6 · The paper itself

Abstract

The Neurospora crassa genome encodes two 1,3-α-glucan synthases. One of these 1,3-α-glucan synthase genes, ags-1, was shown to be required for the synthesis of 1,3-α-glucan in the aerial hyphae and macroconidia cell walls. 1,3-α-Glucan was found in the conidia cell wall, but was absent from the vegetative hyphae cell wall. Deletion of ags-1 affected conidial development. Δags-1 produced only 5 % as many conidia as the WT and most of the conidia produced by Δags-1 were not viable. The ags-1 upstream regulatory elements were shown to direct cell-type-specific expression of red fluorescent protein in conidia and aerial hyphae. A haemagglutinin-tagged AGS-1 was found to be expressed in aerial hyphae and conidia. The research showed that 1,3-α-glucan is an aerial hyphae and conidia cell wall component, and is required for normal conidial differentiation.

Indexed as

Cell WallFungal ProteinsGlucansGlucosyltransferasesHyphaeMolecular Sequence DataNeurospora crassaSpores, FungalFungal ProteinsGlucansglucan synthaseGlucosyltransferases

Identifiers

PMID24847001
PMCPMC4117219
OpenAlexW2023805444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.