ReviewCurrent opinion in genetics & development2014
Epigenetic inheritance of metabolic state.
Review in Current opinion in genetics & development, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Ancestral bisphenol A exposure led to non-alcoholic fatty liver disease and sex-specific alterations in proline and bile metabolism pathways in the liver.Environmental toxicology and chemistry · 2025Article
- Article
- Epigenetic developmental programming and intergenerational effects of thyroid hormones.Vitamins and hormones · 2023Review
- Transgenerational effects of grandparental and parental diets combine with early-life learning to shape adaptive foraging phenotypes in Amblyseius swirskii.Communications biology · 2022Article
- The regulation mechanisms and the Lamarckian inheritance property of DNA methylation in animals.Mammalian genome : official journal of the International Mammalian Genome Society · 2021Review
- The Glucagon-Like Adipokinetic Hormone inFrontiers in physiology · 2021Review
- Low-dose Bisphenol-A Promotes Epigenetic Changes atNutrients · 2020Article
- Article
- Transgenerational Epigenetic Inheritance Is Negatively Regulated by the HERI-1 Chromodomain Protein.Genetics · 2018Article
- Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Nature communications · 2018Article
- Developmental diet regulates Drosophila lifespan via lipid autotoxins.Nature communications · 2017Article
- Parental obesity leads to metabolic changes in the F2 generation inMolecular metabolism · 2017Article
- Article
- The Epigenetic Cytocrin Pathway to the Nucleus. Epigenetic Factors, Epigenetic Mediators, and Epigenetic Traits. A Biochemist Perspective.Frontiers in genetics · 2017Article
- Environmentally induced epigenetic toxicity: potential public health concerns.Critical reviews in toxicology · 2016Review
- Bisphenol-A and metabolic diseases: epigenetic, developmental and transgenerational basis.Environmental epigenetics · 2016Review
- Nutrient regulation of gene expression by O-GlcNAcylation of chromatin.Current opinion in chemical biology · 2016Review
- Article
- Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring.Mammalian genome : official journal of the International Mammalian Genome Society · 2016Article
- Genetic and Sex-Specific Transgenerational Effects of a High Fat Diet in Drosophila melanogaster.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
As the incidence of complex metabolic disease increases in developed countries, so too does the need to understand the causes and risk factors for these disorders. In addition to the well-known contribution of genetics and environment to metabolic dysfunction, many studies have demonstrated that a significant degree of non-genetic heritable risk can be transmitted from parents to offspring over multiple generations. Understanding the mechanisms by which this occurs could change how we study and treat complex metabolic disorders. In this review, we summarize recent advances in this field utilizing Drosophila, mice, and humans, and propose potential molecular mechanisms that underlie the transgenerational inheritance of metabolic state.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.