ArticleHeart rhythm2014
Body surface localization of left and right atrial high-frequency rotors in atrial fibrillation patients: a clinical-computational study.
Article in Heart rhythm, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2018Guideline
- 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2018Guideline
- Guideline
- Systematic differences of non-invasive dominant frequency estimation compared to invasive dominant frequency estimation in atrial fibrillation.Computers in biology and medicine · 2019Trial
- Towards mechanisms-driven strategy for persistent atrial fibrillation ablation: Leveraging digital twins.Journal of precision medicine (Amsterdam, Netherlands) · 2026Article
- Atrial Fibrillation Treatment Stratification Based on Artificial Intelligence-Driven Analysis of the Electrophysiological Complexity.Journal of cardiovascular electrophysiology · 2025Article
- EFFECTS OF TORSO IMPEDANCE ON IN SILICO VOLTAGE MAPPING OF CARDIAC DIPOLES OF ROTORS.Annual Modeling and Simulation Conference (ANNSIM). Annual Modeling and Simulation Conference (Online) · 2025Article
- Complexity and recurrence of body surface electrocardiograms correlate with estimated reentrant atrial activity using electrocardiographic imaging in atrial fibrillation patients.BMC cardiovascular disorders · 2025Article
- ECG electrode localization using 3D visual reconstruction.Frontiers in physiology · 2025Article
- What determines the optimal pharmacological treatment of atrial fibrillation? Insights from in silico trials in 800 virtual atria.The Journal of physiology · 2023Article
- Association with the nonparoxysmal atrial fibrillation duration and outcome of ExTRa Mapping-guided rotor ablation.Journal of arrhythmia · 2023Article
- The spatiotemporal electrogram dispersion ablation targeting rotors is more effective for elderly patients than non-elderly population.Journal of arrhythmia · 2023Article
- Electrocardiographic imaging in the atria.Medical & biological engineering & computing · 2023Review
- TIME- AND FREQUENCY-BASED INDEPENDENT EVALUATION OF QRST CANCELLATION TECHNIQUES FOR SINGLE-LEAD ELECTROCARDIOGRAMS DURING ATRIAL FIBRILLATION.Annual Modeling and Simulation Conference (ANNSIM). Annual Modeling and Simulation Conference (Online) · 2022Article
- Future Directions for Mapping Atrial Fibrillation.Arrhythmia & electrophysiology review · 2022Review
- Simultaneous Whole-Chamber Non-contact Mapping of Highest Dominant Frequency Sites During Persistent Atrial Fibrillation: A Prospective Ablation Study.Frontiers in physiology · 2022Article
- Panoramic Endocardial Optical Mapping Demonstrates Serial Rotors Acceleration and Increasing Complexity of Activity During Onset of Cholinergic Atrial Fibrillation.Journal of the American Heart Association · 2021Article
- Ultrafast four-dimensional imaging of cardiac mechanical wave propagation with sparse optoacoustic sensing.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Novel approaches to mechanism-based atrial fibrillation ablation.Cardiovascular research · 2021Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundAblation is an effective therapy in patients with atrial fibrillation (AF) in which an electrical driver can be identified.
objectiveThe aim of this study was to present and discuss a novel and strictly noninvasive approach to map and identify atrial regions responsible for AF perpetuation.
methodsSurface potential recordings of 14 patients with AF were recorded using a 67-lead recording system. Singularity points (SPs) were identified in surface phase maps after band-pass filtering at the highest dominant frequency (HDF). Mathematical models of combined atria and torso were constructed and used to investigate the ability of surface phase maps to estimate rotor activity in the atrial wall.
resultsThe simulations show that surface SPs originate at atrial SPs, but not all atrial SPs are reflected at the surface. Stable SPs were found in AF signals during 8.3% ± 5.7% vs. 73.1% ± 16.8% of the time in unfiltered vs. HDF-filtered patient data, respectively (P < .01). The average duration of each rotational pattern was also lower in unfiltered than in HDF-filtered AF signals (160 ± 43 ms vs. 342 ± 138 ms; P < .01), resulting in 2.8 ± 0.7 rotations per rotor. Band-pass filtering reduced the apparent meandering of surface HDF rotors by reducing the effect of the atrial electrical activity occurring at different frequencies. Torso surface SPs representing HDF rotors during AF were reflected at specific areas corresponding to the fastest atrial location.
conclusionPhase analysis of surface potential signals after HDF filtering during AF shows reentrant drivers localized to either the left atrium or the right atrium, helping in localizing ablation targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.