ArticleBurns : journal of the International Society for Burn Injuries2014
Predicting mortality from burns: the need for age-group specific models.
Article in Burns : journal of the International Society for Burn Injuries, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Propranolol Reduces Cardiac Index But does not Adversely Affect Peripheral Perfusion in Severely Burned Children.Shock (Augusta, Ga.) · 2016Trial
- Predictors of Mortality and Outcomes in Older Adult Burn Patient Subgroups: A Comparative Meta-analysis of Age, Burn Severity, and Intervention Strategies.Plastic and reconstructive surgery. Global open · 2026Article
- Impaired intestinal cell proliferation parallels increased senescence after burn injury in aged mice.American journal of physiology. Gastrointestinal and liver physiology · 2026Article
- Burn Injuries Accelerate Biological Aging and Increase the Epigenetically Inferred Risk of Mortality and Frailty.Aging and disease · 2025Article
- Advanced Age Worsens Respiratory Function and Pulmonary Inflammation After Burn Injury and This Correlates With Changes in the Fecal Microbiome in Mice.Journal of burn care & research : official publication of the American Burn Association · 2025Article
- Factors affecting intensive care length of stay in critically ill pediatric patients with burn injuries.Pediatric surgery international · 2024Article
- Reducing the excessive inflammation after burn injury in aged mice by maintaining a healthier intestinal microbiome.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Best of Both Worlds: Bridging One Model for All and Group-Specific Model Approaches using Ensemble-based Subpopulation Modeling.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024Article
- Clinical Profile of Children with Burns in a Tertiary Care Hospital.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023Article
- [Research advances on prognosis-related forecasting models for burn patients].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Article
- Risk Models to Predict Mortality in Burn Patients: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2022Article
- Comparative Analysis of Composite Mortality Prediction Scores in Intensive Care Burn Patients.International journal of environmental research and public health · 2022Article
- Age and Injury Size Influence the Magnitude of Fecal Dysbiosis in Adult Burn Patients.Journal of burn care & research : official publication of the American Burn Association · 2022Article
- Prognostic Factors for In-Hospital Mortality of Geriatric Burns From the US National Inpatient Sample 2016 to 2018.Journal of burn care & research : official publication of the American Burn Association · 2022Article
- Risk Factors For Death And Prognosis Value Of Revised Baux Score For Burn Patients With Inhalation Injury.Annals of burns and fire disasters · 2022Article
- Epidemiological and clinical characteristics and outcomes of inpatient burn injuries in older adults: Factors associated with mortality.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- [Establishment of an early risk prediction model for bloodstream infection and analysis of its predictive value in patients with extremely severe burns].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021Article
- Advanced age heightens hepatic damage in a murine model of scald burn injury.The journal of trauma and acute care surgery · 2021Article
- Re-evaluation of the Effect of Age on In-hospital Burn Mortality in a Resource-Limited Setting.The Journal of surgical research · 2021Article
- Prognosis value of revised Baux score among burn patients in developing country.International journal of burns and trauma · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Traditional burn mortality models are derived using all age groups. We hypothesized that age variably impacts mortality after burn and that age-specific models for children, adults, and seniors will more accurately predict mortality than an all-ages model. We audited data from the American Burn Association (ABA) National Burn Repository (NBR) from 2000 to 2009 and used mixed effect logistic regression models to assess the influence of age, total body surface area (TBSA) burn, and inhalation injury on mortality. Mortality models were constructed for all ages and age-specific models: children (<18 years), adults (18-60 years), and seniors (>60 years). Model performance was assessed by area under the receiver operating curve (AUC). Main effect and two-way interactions were used to construct age-group specific mortality models. Each age-specific model was compared to the All Ages model. Of 286,293 records 100,051 had complete data. Overall mortality was 4% but varied by age (17% seniors, <1% children). Age, TBSA, and inhalation injury were significant mortality predictors for all models (p<0.05). Differences in predicted mortality between the All Ages model and the age-specific models occurred in children and seniors. In the age-specific pediatric model, predicted mortality decreased with age; inhalation injury had greater effect on mortality than in the All Ages model. In the senior model mortality increased with age. Seniors had greater increase in mortality per 1% increment in burn size and 1 year increase in age than other ages. The predicted mortality in seniors using the senior-specific model was higher than in the All Ages model. "One size fits all" models for predicting burn outcomes do not accurately reflect the outcomes for seniors and children. Age-specific models for children and seniors may be advisable.
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