Trial reportBiometrics2014
Assessing effects of cholera vaccination in the presence of interference.
Trial report in Biometrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Spillover effects on health outcomes in low- and middle-income countries: a systematic review.International journal of epidemiology · 2017Pooled it
- Bipartite interference and air pollution transport: estimating health effects of power plant interventions.Biostatistics (Oxford, England) · 2025Article
- Design of egocentric network-based studies to estimate causal effects under interference.Statistical methods in medical research · 2025Article
- Designs for Vaccine Studies.Annual review of statistics and its application · 2025Article
- Efficient Nonparametric Estimation of Stochastic Policy Effects with Clustered Interference.Journal of the American Statistical Association · 2025Article
- CAUSAL HEALTH IMPACTS OF POWER PLANT EMISSION CONTROLS UNDER MODELED AND UNCERTAIN PHYSICAL PROCESS INTERFERENCE.The annals of applied statistics · 2024Article
- Article
- Revisiting the effects of maternal education on adolescents' academic performance: Doubly robust estimation in a network-based observational study.Journal of the Royal Statistical Society. Series C, Applied statistics · 2024Article
- Generalized propensity score approach to causal inference with spatial interference.Biometrics · 2023Article
- Methods for Assessing Spillover in Network-Based Studies of HIV/AIDS Prevention among People Who Use Drugs.Pathogens (Basel, Switzerland) · 2023Article
- Propensity Score in the Face of Interference: Discussion of.Observational studies · 2023Article
- Targeted maximum likelihood estimation of causal effects with interference: A simulation study.Statistics in medicine · 2022Article
- Toward evaluation of disseminated effects of medications for opioid use disorder within provider-based clusters using routinely-collected health data.Statistics in medicine · 2022Article
- Inverse probability weighted estimators of vaccine effects accommodating partial interference and censoring.Biometrics · 2022Article
- Inference is bliss: Simulation for power estimation for an observational study of a cholera outbreak intervention.PLoS neglected tropical diseases · 2022Observational
- Estimating Population-Level Effects of the Acellular Pertussis Vaccine Using Routinely Collected Immunization Data.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- A Review of Spatial Causal Inference Methods for Environmental and Epidemiological Applications.International statistical review = Revue internationale de statistique · 2021Article
- Assortativity and Bias in Epidemiologic Studies of Contagious Outcomes: A Simulated Example in the Context of Vaccination.American journal of epidemiology · 2021Article
- Variance estimation in inverse probability weighted Cox models.Biometrics · 2021Article
- Bipartite Causal Inference with Interference.Statistical science : a review journal of the Institute of Mathematical Statistics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
Interference occurs when the treatment of one person affects the outcome of another. For example, in infectious diseases, whether one individual is vaccinated may affect whether another individual becomes infected or develops disease. Quantifying such indirect (or spillover) effects of vaccination could have important public health or policy implications. In this article we use recently developed inverse-probability weighted (IPW) estimators of treatment effects in the presence of interference to analyze an individually-randomized, placebo-controlled trial of cholera vaccination that targeted 121,982 individuals in Matlab, Bangladesh. Because these IPW estimators have not been employed previously, a simulation study was also conducted to assess the empirical behavior of the estimators in settings similar to the cholera vaccine trial. Simulation study results demonstrate the IPW estimators can yield unbiased estimates of the direct, indirect, total, and overall effects of vaccination when there is interference provided the untestable no unmeasured confounders assumption holds and the group-level propensity score model is correctly specified. Application of the IPW estimators to the cholera vaccine trial indicates the presence of interference. For example, the IPW estimates suggest on average 5.29 fewer cases of cholera per 1000 person-years (95% confidence interval 2.61, 7.96) will occur among unvaccinated individuals within neighborhoods with 60% vaccine coverage compared to neighborhoods with 32% coverage. Our analysis also demonstrates how not accounting for interference can render misleading conclusions about the public health utility of vaccination.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.