ArticleCurrent biology : CB2014
Evolution: the advantage of 'maladaptive' pain plasticity.
Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Sex differences in the relationship between pain and autonomic outflow during a cold pressor test.Biology of sex differences · 2025Article
- Review
- A challenging diagnosis of chronic osteomyelitis in a child with congenital insensitivity to pain: a case report.Annals of medicine and surgery (2012) · 2024Article
- Article
- Glucocorticoid Hormones as Modulators of the Kynurenine Pathway in Chronic Pain Conditions.Cells · 2023Review
- Chloride-dependent mechanisms of multimodal sensory discrimination and nociceptive sensitization ineLife · 2023Article
- Perspectives on the insidious nature of pain metaphor: we literally need to change our metaphors.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- Enhanced nociceptive behavior and expansion of associated primary afferents in a rabbit model of cerebral palsy.Journal of neuroscience research · 2022Article
- The Landscape of Chronic Pain: Broader Perspectives.Medicina (Kaunas, Lithuania) · 2019Review
- How evolutionary psychiatry can advance psychopharmacology .Dialogues in clinical neuroscience · 2019Article
- Nociceptive Biology of Molluscs and Arthropods: Evolutionary Clues About Functions and Mechanisms Potentially Related to Pain.Frontiers in physiology · 2018Review
- Intra-axonal protein synthesis in development and beyond.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2016Review
- Clinical features for diagnosis and management of patients with PRDM12 congenital insensitivity to pain.Journal of medical genetics · 2016Article
- Article
- Commonalities between pain and memory mechanisms and their meaning for understanding chronic pain.Progress in molecular biology and translational science · 2015Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Following injury, nociceptive systems become sensitized, leading to heightened pain perception. The evolutionary reason for this phenomenon has been hard to pinpoint. A study in squid now suggests that nociceptive sensitization enhances survival from predators.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.