ArticleJournal of biosciences2014
MiRNAting control of DNA methylation.
Article in Journal of biosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Construction of a DNA Methylation Map of Argali Hybrid Sheep During Mo Infection.Microorganisms · 2026Article
- Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025Review
- From chromatin to crop: epigenetic innovations in bioenergy systems.Frontiers in plant science · 2025Review
- Comprehensive analysis of computational approaches in plant transcription factors binding regions discovery.Heliyon · 2024Article
- PTFSpot: deep co-learning on transcription factors and their binding regions attains impeccable universality in plants.Briefings in bioinformatics · 2024Article
- Article
- Epigenetics at the crossroads of secondary growth regulation.Frontiers in plant science · 2022Review
- Identification, evolution, expression analysis of phospholipase D (PLD) gene family in tea (Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- F-box protein CFK1 interacts with and degrades de novo DNA methyltransferase in Arabidopsis.The New phytologist · 2021Article
- MicroRNAs as potential targets for improving rice yield via plant architecture modulation: Recent studies and future perspectives.Journal of biosciences · 2020Article
- Extensive transcriptomic and epigenomic remodelling occurs during Arabidopsis thaliana germination.Genome biology · 2017Article
- Loss of function of Arabidopsis microRNA-machinery genes impairs fertility, and has effects on homologous recombination and meiotic chromatin dynamics.Scientific reports · 2017Article
- The role of microRNA in nutritional control.Journal of internal medicine · 2015Article
- A Deluge of Complex Repeats: The Solanum Genome.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA methylation is a type of epigenetic modification where a methyl group is added to the cytosine or adenine residue of a given DNA sequence. It has been observed that DNA methylation is achieved by some collaborative agglomeration of certain proteins and non-coding RNAs. The assembly of IDN2 and its homologous proteins with siRNAs recruits the enzyme DRM2, which adds a methyl group at certain cytosine residues within the DNA sequence. In this study, it was found that de novo DNA methylation might be regulated by miRNAs through systematic targeting of the genes involved in DNA methylation. A comprehensive genome-wide and system-level study of miRNA targeting, transcription factors, DNA-methylation-causing genes and their target genes has provided a clear picture of an interconnected relationship of all these factors which regulate DNA methylation in Arabidopsis. The study has identified a DNA methylation system that is controlled by four different genes: IDN2, IDNl1, IDNl2 and DRM2. These four genes along with various critical transcription factors appear to be controlled by five different miRNAs. Altogether, DNA methylation appears to be a finely tuned process of opposite control systems of DNAmethylation- causing genes and certain miRNAs pitted against each other.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.