Evidence map›Paper›PMID 24845400›Full record

ArticleNature communications2014

Terminal supraparticle assemblies from similarly charged protein molecules and nanoparticles.

Jai Il Park, Trung Dac Nguyen, Gleiciani de Queirós Silveira, Joong Hwan Bahng, Sudhanshu Srivastava, Gongpu Zhao, Kai Sun, Peijun Zhang, Sharon C Glotzer, Nicholas A Kotov

Abstract read
In one paragraph

Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Tapered chiral nanoparticles as broad-spectrum thermally stable antivirals for SARS-CoV-2 variants.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Protein Assembly by Design.Chemical reviews · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Chiral Supraparticles for Controllable Nanomedicine.Advanced materials (Deerfield Beach, Fla.) · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jai Il Park1] Departments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [2] [3].
Trung Dac Nguyen1] Departments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [2].
Gleiciani de Queirós SilveiraDepartments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Joong Hwan BahngBiomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Sudhanshu SrivastavaDepartments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Gongpu ZhaoDepartment of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA.
Kai SunMaterials Science and Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Peijun ZhangDepartment of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA.
Sharon C Glotzer1] Departments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [2] Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [3] Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan 48019, USA.
Nicholas A Kotov1] Departments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [2] Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [3] Materials Science and Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA [4] Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan 48019, USA.

Funding

X-Ray Core P50GM082251 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CALERO, GUILLERMO ALBERTO · 2007 to 2018
$48.1M
Structure and function of membrane receptor signaling complex in bacterial chemotR01GM085043 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHANG, PEIJUN · 2009 to 2013
$1.4M
NIGMS NIH HHS GM085043NIGMS NIH HHS P50 GM082251NIGMS NIH HHS R01 GM085043
6 · The paper itself

Abstract

Self-assembly of proteins and inorganic nanoparticles into terminal assemblies makes possible a large family of uniformly sized hybrid colloids. These particles can be compared in terms of utility, versatility and multifunctionality to other known types of terminal assemblies. They are simple to make and offer theoretical tools for designing their structure and function. To demonstrate such assemblies, we combine cadmium telluride nanoparticles with cytochrome C protein and observe spontaneous formation of spherical supraparticles with a narrow size distribution. Such self-limiting behaviour originates from the competition between electrostatic repulsion and non-covalent attractive interactions. Experimental variation of supraparticle diameters for several assembly conditions matches predictions obtained in simulations. Similar to micelles, supraparticles can incorporate other biological components as exemplified by incorporation of nitrate reductase. Tight packing of nanoscale components enables effective charge and exciton transport in supraparticles and bionic combination of properties as demonstrated by enzymatic nitrate reduction initiated by light absorption in the nanoparticle.

Indexed as

Cadmium CompoundsColloidsCytochromes cHumansMetal NanoparticlesMolecular Docking SimulationNitrate ReductasePichiaStatic ElectricityTelluriumCadmium Compoundscadmium tellurideColloidsCytochromes cNitrate ReductaseTellurium

Identifiers

PMID24845400
PMCPMC4405188

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.