PEG molecular net-cloth grafted on polymeric substrates and its bio-merits.

Changwen Zhao, Zhifeng Lin, Huabing Yin, Yuhong Ma, Fujian Xu, Wantai Yang

Abstract read

In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

A Self-Folding Hydrogel In Vitro Model for Ductal Carcinoma.Tissue engineering. Part C, Methods · 2016
Article
Net-Immobilization of β-glucosidase on Nonwoven Fabrics to Lower the Cost of "Cellulosic Ethanol" and Increase Cellulose Conversions.Scientific reports · 2016
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Changwen Zhao1] State Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China [2] Key Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China.

Zhifeng LinState Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China.

Huabing YinCollege of Science and Engineering, Division of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow, United Kingdom.

Yuhong MaKey Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China.

Fujian Xu1] State Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China [2] Key Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China.

Wantai Yang1] State Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China [2] Key Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer brushes and hydrogels are sensitive to the environment, which can cause uncontrolled variations on their performance. Herein, for the first time, we report a non-swelling "PEG molecular net-cloth" on a solid surface, fabricated using a novel "visible light induced surface controlled graft cross-linking polymerization" (VSCGCP) technique. Via this method, we show that 1) the 3D-network structure of the net-cloth can be precisely modulated and its thickness controlled; 2) the PEG net-cloth has excellent resistance to non-specific protein adsorption and cell adhesion; 3) the mild polymerization conditions (i.e. visible light and room temperature) provided an ideal tool for in situ encapsulation of delicate biomolecules such as enzymes; 4) the successive grafting of reactive three-dimensional patterns on the PEG net-cloth enables the creation of protein microarrays with high signal to noise ratio. Importantly, this strategy is applicable to any C-H containing surface, and can be easily tailored for a broad range of applications.

Indexed as

AdsorptionCell AdhesionEnzymes, ImmobilizedGlucoseHorseradish PeroxidaseHumansHydrogelsPolyethylene GlycolsPolymerizationPolymersProtein Array AnalysisSurface PropertiesEnzymes, ImmobilizedGlucoseglucose pentaacetateHorseradish PeroxidaseHydrogelsPolyethylene GlycolsPolymers

Identifiers

PMID24845078

DOI10.1038/srep04982

PMCPMC4028697

What OpenQuestion holds

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.