Evidence map›Paper›PMID 24844772›Full record

Trial reportPloS one2014

Feasibility of a combined aerobic and strength training program and its effects on cognitive and physical function in institutionalized dementia patients. A pilot study.

Willem J R Bossers, Erik J A Scherder, Froukje Boersma, Tibor Hortobágyi, Lucas H V van der Woude, Marieke J G van Heuvelen

Abstract readClinical Trial, Phase IClinical Trial, Phase II
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Physical and Motor Fitness Tests for Older Adults Living in Nursing Homes: A Systematic Review.International journal of environmental research and public health · 2022
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  13. Recommendations for assessing motor performance in individuals with dementia: suggestions of an expert panel - a qualitative approach.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Willem J R BossersUniversity of Groningen, University Medical Center Groningen, Center for Human Movement Sciences, Groningen, The Netherlands.
Erik J A ScherderUniversity of Groningen, University Medical Center Groningen, Center for Human Movement Sciences, Groningen, The Netherlands; VU University, Department of Clinical Neuropsychology, Amsterdam, The Netherlands.
Froukje BoersmaUniversity of Groningen, University Medical Center Groningen, Department of General Practice, Elderly Care Medicine, Groningen, The Netherlands.
Tibor HortobágyiUniversity of Groningen, University Medical Center Groningen, Center for Human Movement Sciences, Groningen, The Netherlands.
Lucas H V van der WoudeUniversity of Groningen, University Medical Center Groningen, Center for Human Movement Sciences, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Center for Rehabilitation, Groningen, The Netherlands.
Marieke J G van HeuvelenUniversity of Groningen, University Medical Center Groningen, Center for Human Movement Sciences, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe examined the feasibility of a combined aerobic and strength training program in institutionalized dementia patients and studied the effects on cognitive and physical function.

methodsThirty-three patients with dementia, recruited from one nursing home, participated in this non-randomized pilot study (25 women; age = 85.2±4.9 years; Mini Mental State Examination = 16.8±4.0). In phase 1 of the study, seventeen patients in the Exercise group (EG) received a combined aerobic and strength training program for six weeks, five times per week, 30 minutes per session, in an individually supervised format and successfully concluded the pre and posttests. In phase 2 of the study, sixteen patients in the Social group (SG) received social visits at the same frequency, duration, and format and successfully concluded the pre and posttests.

resultsIndices of feasibility showed that the recruitment and adherence rate, respectively were 46.2% and 86.3%. All EG patients completed the exercise program according to protocol without adverse events. After the six-week program, no significant differences on cognitive function tests were found between the EG and SG. There was a moderate effect size in favor for the EG for the Visual Memory Span Forward; a visual attention test. There were significant differences between groups in favor for the EG with moderate to large effects for the physical tests Walking Speed (p = .003), Six-Minute Walk Test (p = .031), and isometric quadriceps strength (p = .012).

conclusionsThe present pilot study showed that it is feasible to conduct a combined aerobic and strength training program in institutionalized patients with dementia. The selective cognitive visual attention improvements and more robust changes in motor function in favor of EG vs. SG could serve as a basis for large randomized clinical trials.

trial registrationtrialregister.nl 1230.

Indexed as

AgedAged, 80 and overDementiaExerciseFemaleHumansMaleNursing HomesPatient CompliancePilot ProjectsResistance Training

Identifiers

PMID24844772
PMCPMC4028210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.