ReviewAllergy, asthma & immunology research2014
Is there a link between obesity and asthma?
Review in Allergy, asthma & immunology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Is Bariatric Surgery Better than Nonsurgical Weight Loss for Improving Asthma Control? A Systematic Review.Obesity surgery · 2021Pooled it
- Obesity's effect on asthma extends to diagnostic criteria.The Journal of allergy and clinical immunology · 2018Trial
- miRNA profiling shows shared signatures in pediatric asthma, obesity and their comorbidity.Frontiers in immunology · 2026Article
- Role of body anthropometry in severe asthmatic patients: Evidences from the Severe Asthma Network in Italy (SANI) registry.The World Allergy Organization journal · 2025Article
- An analysis of the global burden of childhood and adolescent asthma attributable to high BMI: 1990-2021.Frontiers in pediatrics · 2025Article
- Chromium and formoterol therapy for obesity-induced asthma in rats.Frontiers in pharmacology · 2025Article
- Life Course of Asthma.Advances in experimental medicine and biology · 2023Article
- Experiences of exercise in patients with asthma: a qualitative analysis of discussions in a UK asthma online community.BJGP open · 2022Article
- Comparison of Pulmonary Function and Inflammation in Children/Adolescents with New-Onset Asthma with Different Adiposity Statuses.Nutrients · 2022Article
- A review on the anesthetic management of obese patients undergoing surgery.BMC anesthesiology · 2022Review
- Plasma lipid biomarkers in relation to BMI, lung function, and airway inflammation in pediatric asthma.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Obesity, malnutrition, and trace element deficiency in the coronavirus disease (COVID-19) pandemic: An overview.Nutrition (Burbank, Los Angeles County, Calif.) · 2021Review
- Association Between Environmental Factors and Asthma Using Mendelian Randomization: Increased Effect of Body Mass Index on Adult-Onset Moderate-to-Severe Asthma Subtypes.Frontiers in genetics · 2021Article
- RNA-Seq Expression Analysis of Chronic Asthmatic Mice with Bu-Shen-Yi-Qi Formula Treatment and Prediction of Regulated Gene Targets of Anti-Airway Remodeling.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Sex differences in the association between asthma incidence and modifiable risk factors in Korean middle-aged and older adults: NHIS-HEALS 10-year cohort.BMC pulmonary medicine · 2019Article
- Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- Obese- and allergic-related asthma phenotypes among children across the United States.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019Article
- CD26 and Asthma: a Comprehensive Review.Clinical reviews in allergy & immunology · 2019Review
- Clinical Implications of Single Nucleotide Polymorphisms in Diagnosis of Asthma and its Subtypes.Yonsei medical journal · 2019Review
- Obesity-Associated Metabolic Signatures Correlate to Clinical and Inflammatory Profiles of Asthma: A Pilot Study.Allergy, asthma & immunology research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing epidemiological data identify a link between obesity and asthma incidence and severity. Based on experimental data, it is possible that shared inflammatory mechanisms play a role in determining this linkage. Although controversial, the role of adipokines may be central to this association and the maintenance of the asthma phenotype. While leptin and adiponectin have a causal link to experimental asthma in mice, data in humans are less conclusive. Recent studies demonstrate that adipokines can regulate the survival and function of eosinophils and that these factors can affect eosinophil trafficking from the bone marrow to the airways. In addition, efferocytosis, the clearance of dead cells, by airway macrophages or blood monocytes appears impaired in obese asthmatics and is inversely correlated with glucocorticoid responsiveness. This review examines the potential mechanisms linking obesity to asthma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.