ReviewJournal of diabetes investigation2014
Cancer biology in diabetes.
Review in Journal of diabetes investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Tirzepatide and Cancer Risk in Individuals with and without Diabetes: A Systematic Review and Meta-Analysis.Endocrinology and metabolism (Seoul, Korea) · 2025 · on this mapPooled it
- Incretins and SGLT-2 inhibitors in diabetic patients with neuroendocrine tumors: current updates and future directions.Reviews in endocrine & metabolic disorders · 2025Review
- Metformin may improve the outcome of patients with colorectal cancer and type 2 diabetes mellitus partly through effects on neutrophil extracellular traps.BJC reports · 2023Article
- Tirzepatide-Friend or Foe in Diabetic Cancer Patients?Biomolecules · 2022Review
- Review
- Cancer Biology and Prevention in Diabetes.Cells · 2020Review
- Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance through the CXCL12/CXCR4/mTOR/TGFβ Signaling Pathway in Breast Cancer Cells.International journal of molecular sciences · 2020Article
- In vitro cytogenetic assessment and comparison of vildagliptin and sitagliptin.Cytotechnology · 2019Article
- Using Mouse andInternational journal of molecular sciences · 2018Review
- Do MCF7 cells cope with metformin treatment under energetic stress in low glucose conditions?Molecular biology reports · 2018Article
- Diabetes Mellitus and Risk of Colorectal Cancer Mortality in Japan: the Japan Collaborative Cohort StudyAsian Pacific journal of cancer prevention : APJCP · 2016Article
- Clinical benefits of metformin in gynecologic oncology.Oncology letters · 2015Article
- Long-term insulin glargine therapy in type 2 diabetes mellitus: a focus on cardiovascular outcomes.Vascular health and risk management · 2015Review
- Recent advances in the use of metformin: can treating diabetes prevent breast cancer?BioMed research international · 2015Review
- Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.BioMed research international · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes is a serious metabolic disease that causes multiple organ dysfunctions. Recent evidence suggests that diabetes could contribute to the initiation and progression of certain cancers in addition to the classic diabetic complications. Furthermore, some of the drugs used clinically to treat patients with diabetes might affect cancer initiation, progression and mortality. The recent discovery of the possible anticancer effects of metformin, a classic antidiabetic drug, has led physicians and scientists to reconsider the interaction between diabetes and cancer. In the present review, we analyze recent reports in this field, and explore possible mechanistic links between diabetes and cancer biology.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.