Evidence map›Paper›PMID 24843719›Full record

ArticleJournal of diabetes investigation2013

Association of glycated albumin with the presence of carotid plaque in patients with type 2 diabetes.

Yuki Sato, Mototsugu Nagao, Akira Asai, Yasushi Nakajima, Makiyo Takaya, Naomi Takeichi, Shuji Takemitsu, Mariko Sudo, Toshiko Kano-Wakakuri, Akira Ishizaki and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  5. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Yuki SatoDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Mototsugu NagaoDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Akira AsaiDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Yasushi NakajimaDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Makiyo TakayaDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Naomi TakeichiDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Shuji TakemitsuDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Mariko SudoDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Toshiko Kano-WakakuriDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Akira IshizakiDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Taro HaradaDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Kyoko Tanimura-InagakiDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Fumitaka OkajimaDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Hideki TamuraDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Hitoshi SugiharaDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Shinichi OikawaDivision of Endocrinology and Metabolism Department of Medicine Nippon Medical School Tokyo Japan.
Nippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionPostprandial hyperglycemia is a potent risk factor for cardiovascular disease. Serum glycated albumin (GA) has been reported to reflect postprandial blood glucose fluctuations. In the present study, we assessed the possible correlation of GA with the presence of carotid plaque to evaluate the potential clinical usefulness of GA for predicting atherosclerotic cardiovascular complications in patients with type 2 diabetes. MATERIALS AND

methodsPatients with type 2 diabetes (n = 236) admitted to Nippon Medical School Hospital (Tokyo, Japan) for glycemic control (aged 19-86 years, 81 females and 155 males) were examined. Clinical measurements were taken on admission. The presence of carotid plaque was assessed by ultrasonography.

resultsIn patients with carotid plaque (n = 154), GA (P = 0.023) was higher than those without carotid plaque (n = 82). In contrast, neither fasting plasma glucose (P = 0.48) nor glycated hemoglobin (P = 0.41) was significantly different between the groups. The results of logistic regression analysis showed that GA (age- and sex-adjusted odds ratio [95% confidence interval], 1.05 [1.01-1.09]; P = 0.017) and glycated hemoglobin (1.17 [1.01-1.37]; P = 0.036) were significantly associated with the presence of carotid plaque.

conclusionsThe positive correlation of serum GA with the presence of carotid plaque in type 2 diabetes suggests that GA will serve as a useful clinical marker for predicting diabetic cardiovascular complications.

Indexed as

Carotid plaqueGlycated albuminType 2 diabetes mellitus

Identifiers

PMID24843719
PMCPMC4020260
OpenAlexW1966594544

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.