Evidence map›Paper›PMID 24843218›Full record

Trial reportActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2014

Stapler suture of the pharynx after total laryngectomy.

R A Dedivitis, F T Aires, E G Pfuetzenreiter, M A F Castro, A V Guimarães

Abstract readClinical TrialComparative Study
PubMed Full text at PMC
In one paragraph

Trial report in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Stapler versus manual closure for pharyngeal repair after total laryngectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Stapler versus conventional pharyngeal repair after total laryngectomy: a randomized clinical trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Trial
  3. Article
  4. Stapler-assisted total laryngectomy and hybrid primary puncture: analysis of functional results.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025
    Article
  5. Article
  6. Article
  7. Pharyngocutaneous Fistula in Salvage Laryngectomy: Use of the Stapler Versus Manual Suturing Technique.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  8. Article
  9. Risk Factors for Pharyngocutaneous Fistula Following Total Laryngectomy.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  10. Stapler Assisted Total Laryngectomy: A Prospective Randomized Clinical Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Evidence and evidence gaps of laryngeal cancer surgery.GMS current topics in otorhinolaryngology, head and neck surgery · 2016
    Review
  16. Pharyngocutaneous fistula following total laryngectomy: analysis of risk factors, prognosis and treatment modalities.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2015
    Review
  17. Analysis of risk factors for pharyngocutaneous fistula after total laryngectomy with particular focus on nutritional status.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2015
    Article
  18. Tracheocutaneous fistula in patients undergoing supracricoid partial laryngectomy: the role of chronic aspiration.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R A DedivitisDepartment of Head and Neck Surgery, Hospital das Clínicas, São Paulo School of Medicine, São Paulo; ; Department of Head and Neck Surgery, Hospital Ana Costa, Santos and Irmandade da Santa Casa de Misericórdia, Santos, Brazil;
F T AiresCentro Universitário Lusíada, Santos, Brazil.
E G PfuetzenreiterDepartment of Head and Neck Surgery, Hospital Ana Costa, Santos and Irmandade da Santa Casa de Misericórdia, Santos, Brazil;
M A F CastroDepartment of Head and Neck Surgery, Hospital Ana Costa, Santos and Irmandade da Santa Casa de Misericórdia, Santos, Brazil;
A V GuimarãesDepartment of Head and Neck Surgery, Hospital Ana Costa, Santos and Irmandade da Santa Casa de Misericórdia, Santos, Brazil;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of a stapler for pharyngeal closure during total laryngectomy was first described in 1971. It provides rapid watertight closure without surgical field contamination. The objective of our study was to compare the incidence of pharyngocutaneous fistula after total laryngectomy with manual and mechanical closures of the pharynx. This was a non-randomised, prospective clinical study conducted at two tertiary medical centres from 1996 to 2011 including consecutive patients with laryngeal tumours who underwent total laryngectomy. We compared the incidence of pharyngocutaneous fistula between two groups of patients: in 20 patients, 75 mm linear stapler closure was applied, whereas in 67 patients a manual suture was used. Clinical data were compared between groups. The groups were statistically similar in terms of gender, age, diabetes mellitus, smoking and alcohol consumption and tumour site. The group of patients who underwent stapler-assisted pharyngeal closure had a higher number of patients with previous tracheotomy (p < 0.001) and previous chemoradiation (p < 0.001). The incidence of pharyngocutaneous fistula was 30% in the mechanical closure group and 20.9% in the manual suture group (p = 0.42). In conclusion the use of the stapler does not increase the rate of fistulae.

Indexed as

SuturesCarcinoma, Squamous CellCutaneous FistulaDigestive System FistulaFemaleHumansLaryngeal NeoplasmsLaryngectomyMaleMiddle AgedPharyngeal DiseasesPharynxProspective StudiesCarcinomaCutaneous fistulaLaryngeal neoplasmsLaryngectomySquamous cellSurgical staplersSuture techniques

Identifiers

PMID24843218
PMCPMC4025176

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.