Evidence map›Paper›PMID 24843032›Full record

ArticleeLife2014

Delivering the second revolution in site-specific nucleases.

Perry B Hackett, Nikunj V Somia

Abstract readComment
In one paragraph

Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Perry B HackettPerry B Hackett is in the Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States hacke004@umn.edu.
Nikunj V SomiaNikunj V Somia is in the Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.

Funding

THERAPY FOR HYPERAMMONEMIA WITH GENETICALLY ENGINEERED BACTERIAP01HD032652 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI WHITLEY, CHESTER B. · 1995 to 2016
$14.5M
NICHD NIH HHS P01 HD032652
6 · The paper itself

Abstract

Viruses have been used to deliver two types of site-specific nucleases into cells for targeted gene editing.

Indexed as

Genetic VectorsGenome, HumanTransduction, GeneticEndonucleasesGenetic EngineeringHumansLentivirusTranscription FactorsTransfectionEndonucleasesTranscription Factorsgaggene therapylentiviral vectorprotein transductiontranscription activator-like effector nucleaseszinc-finger nucleases

Identifiers

PMID24843032
PMCPMC4013716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.