ArticleHypertension (Dallas, Tex. : 1979)2014
Association of parity with carotid diameter and distensibility: multi-ethnic study of atherosclerosis.
Article in Hypertension (Dallas, Tex. : 1979), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Trial
- Endocrine enigmas: vascular health in females throughout the lifespan.American journal of physiology. Heart and circulatory physiology · 2025Review
- Reproductive Factors Linked With Myocardial Fibrosis: MESA (Multi-Ethnic Study of Atherosclerosis).JACC. Advances · 2023Article
- The EVA (Early Vascular Aging) Study: Association of Central Obesity With Worse Arterial Health After Preeclampsia.Journal of the American Heart Association · 2023Article
- Female-specific risk factors of parity and menopause age and risk of carotid plaque: the multi-ethnic study of atherosclerosis.American journal of cardiovascular disease · 2023Article
- Association of Vascular Properties With the Brain White Matter Hyperintensity in Middle-Aged Population.Journal of the American Heart Association · 2022Article
- The Association Between Multiparity and Adipokine Levels: The Multi-Ethnic Study of Atherosclerosis.Journal of women's health (2002) · 2022Article
- Association between parity and markers of inflammation: The multi-ethnic study of atherosclerosis.Frontiers in cardiovascular medicine · 2022Article
- High Prevalence of Asymptomatic Intracranial Atherosclerosis in Elder Women With Tubal Ligation: Result From a Community-Based Study in Shandong, China.Frontiers in cardiovascular medicine · 2022Article
- Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery.Journal of pharmacokinetics and pharmacodynamics · 2020Article
- Identification of female-specific risk enhancers throughout the lifespan of women to improve cardiovascular disease prevention.American journal of preventive cardiology · 2020Review
- Parity is associated with albuminuria and chronic kidney disease: a population-based study.Aging · 2019Article
- Multiparity is associated with poorer cardiovascular health among women from the Multi-Ethnic Study of Atherosclerosis.American journal of obstetrics and gynecology · 2019Article
- Brachial artery stiffening in healthy primigravidas is associated with weight gain and increased cardiac output.Hypertension in pregnancy · 2018Article
- Article
- Is there a differential impact of parity on factors regulating maternal peripheral resistance?Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- The Relationship of Restless Legs Syndrome to History of Pregnancy-Induced Hypertension.Journal of women's health (2002) · 2016Article
- Parity and Risk of Coronary Heart Disease in Middle-aged and Older Chinese Women.Scientific reports · 2015Article
- Association of sex hormones with carotid artery distensibility in men and postmenopausal women: multi-ethnic study of atherosclerosis.Hypertension (Dallas, Tex. : 1979) · 2015Article
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Authors and funding
6 authors.
Funding
Abstract
Pregnancy and childbirth are associated with hemodynamic changes and vascular remodeling. It is not known whether parity is associated with later adverse vascular properties such as larger arterial diameter, wall thickness, and lower distensibility. We used baseline data from 3283 women free of cardiovascular disease aged 45 to 84 years enrolled in the population-based Multi-Ethnic Study of Atherosclerosis. Participants self-reported parity status. Ultrasound-derived carotid artery lumen diameters and brachial artery blood pressures were measured at peak-systole and end-diastole. Common carotid intima-media thickness was also measured. Regression models to determine the association of carotid distensibility coefficient, lumen diameter, and carotid intima-media thickness with parity were adjusted for age, race, height, weight, diabetes mellitus, current smoking, blood pressure medication use, and total and high-density lipoprotein cholesterol levels. The prevalence of nulliparity was 18%. In adjusted models, carotid distensibility coefficient was 0.09×10−5 Pa−1 lower (P=0.009) in parous versus nulliparous women. Among parous women, there was a nonlinear association with the greatest carotid distensibility coefficient seen in women with 2 live births and significantly lower distensibility seen in primiparas (P=0.04) or with higher parity >2 (P=0.005). No such pattern of association with parity was found for lumen diameter or carotid intima-media thickness. Parity is associated with lower carotid artery distensibility, suggesting arterial remodeling that lasts beyond childbirth. These long-term effects on the vasculature may explain the association of parity with cardiovascular events later in life.
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