Evidence map›Paper›PMID 24842881›Full record

ArticleThe American journal of tropical medicine and hygiene2014

Water filter provision and home-based filter reinforcement reduce diarrhea in Kenyan HIV-infected adults and their household members.

Patricia B Pavlinac, Jaqueline M Naulikha, Linda Chaba, Naomi Kimani, Laura R Sangaré, Krista Yuhas, Benson O Singa, Grace John-Stewart, Judd L Walson

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Interventions to improve water quality for preventing diarrhoea.The Cochrane database of systematic reviews · 2015
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Patricia B PavlinacDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington ppav@uw.edu.
Jaqueline M NaulikhaDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Linda ChabaDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Naomi KimaniDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Laura R SangaréDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Krista YuhasDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Benson O SingaDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Grace John-StewartDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
Judd L WalsonDepartment of Epidemiology, University of Washington, Seattle, Washington; Kenya Medical Research Institute, Centre for Clinical Research, Nairobi, Kenya; Department of Pediatrics, University of Washington, Seattle, Washington; Department of Global Health, University of Washington, Seattle, Washington; Center for AIDS Research Biometrics Core, University of Washington, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington.
University of Washington · USSeattle University · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Pediatric HIV-1 in Africa: Pathogenesis and ManagementK24HD054314 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C. · 2006 to 2016
$1.2M
NIAID NIH HHS P30 AI027757NIAID NIH HHS T32 AI007140NICHD NIH HHS K24 HD054314
6 · The paper itself

Abstract

Among human immunodeficiency virus (HIV)-infected adults and children in Africa, diarrheal disease remains a major cause of morbidity and mortality. We evaluated the effectiveness of provision and home-based reinforcement of a point-of-use water filtration device to reduce diarrhea among 361 HIV-infected adults in western Kenya by comparing prevalence of self-reported diarrhea before and after these interventions. After provision of the filter, 8.7% of participants reported diarrhea compared with 17.2% in the 3 months before filter provision (odds ratio [OR] = 0.39, 95% confidence interval [95% CI] = 0.23-0.66, P < 0.001). The association was similar among 231 participants who were already taking daily cotrimoxazole prophylaxis before being given a filter (OR = 0.47, 95% CI = 0.25-0.88, P = 0.019). Educational reinforcement was also associated with a modest reduction in self-reported diarrhea (OR = 0.50, 95% CI = 0.20-0.99, P = 0.047). Provision and reinforcement of water filters may confer significant benefit in reducing diarrhea among HIV-infected persons, even when cotrimoxazole prophylaxis is already being used.

Indexed as

HIVWater PurificationAdultAnti-Infective AgentsCoinfectionDiarrheaDrinking WaterFemaleFiltrationHIV InfectionsHumansKenyaMalePrevalenceTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Infective AgentsDrinking WaterTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID24842881
PMCPMC4125248
OpenAlexW2014532830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.