ArticlePloS one2014
Insights from the genome annotation of Elizabethkingia anophelis from the malaria vector Anopheles gambiae.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Mortality Risk and Antibiotic Therapy for Patients with Infections Caused byMedicina (Kaunas, Lithuania) · 2024Pooled it
- Influence of the Origin, Feeding Status, andBiology · 2025Article
- Role of microbiota in host-Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Review
- Genomic profiling ofFrontiers in microbiology · 2025Article
- Microbial gatekeepers: midgut bacteria inFrontiers in microbiology · 2025Review
- Molecular characterization, comparative genome analysis and resistance determinants of three clinicalFrontiers in microbiology · 2025Article
- MosAIC: An annotated collection of mosquito-associated bacteria with high-quality genome assemblies.PLoS biology · 2024Article
- Article
- Characterization of the Tissue and Strain-Specific Microbiota ofTropical medicine and infectious disease · 2024Article
- Article
- Review on infection control strategies to minimize outbreaks of the emerging pathogen Elizabethkingia anophelis.Antimicrobial resistance and infection control · 2023Review
- Egg-laying by female Aedes aegypti shapes the bacterial communities of breeding sites.BMC biology · 2023Article
- Multi-Drug-Resistant Elizabethkingia meningoseptica: A Rare Cause of Late-Onset Sepsis in a Preterm Neonate.Cureus · 2023Article
- Elizabethkingia anophelis Infections: A Case Series From a Tertiary Care Hospital in Uttar Pradesh.Cureus · 2022Article
- Proteomic Network of Antibiotic-Induced Outer Membrane Vesicles Released by Extensively Drug-Resistant Elizabethkingia anophelis.Microbiology spectrum · 2022Article
- Epidemiology and Characteristics ofMicroorganisms · 2022Review
- The Integrative and Conjugative Element ICEMicrobiology spectrum · 2021Article
- Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus.Parasites & vectors · 2021Article
- Microbiota identified from preserved Anopheles.Malaria journal · 2021Article
- Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1.Scientific reports · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Elizabethkingia anophelis is a dominant bacterial species in the gut ecosystem of the malaria vector mosquito Anopheles gambiae. We recently sequenced the genomes of two strains of E. anophelis, R26T and Ag1, isolated from different strains of A. gambiae. The two bacterial strains are identical with a few exceptions. Phylogenetically, Elizabethkingia is closer to Chryseobacterium and Riemerella than to Flavobacterium. In line with other Bacteroidetes known to utilize various polymers in their ecological niches, the E. anophelis genome contains numerous TonB dependent transporters with various substrate specificities. In addition, several genes belonging to the polysaccharide utilization system and the glycoside hydrolase family were identified that could potentially be of benefit for the mosquito carbohydrate metabolism. In agreement with previous reports of broad antibiotic resistance in E. anophelis, a large number of genes encoding efflux pumps and β-lactamases are present in the genome. The component genes of resistance-nodulation-division type efflux pumps were found to be syntenic and conserved in different taxa of Bacteroidetes. The bacterium also displays hemolytic activity and encodes several hemolysins that may participate in the digestion of erythrocytes in the mosquito gut. At the same time, the OxyR regulon and antioxidant genes could provide defense against the oxidative stress that is associated with blood digestion. The genome annotation and comparative genomic analysis revealed functional characteristics associated with the symbiotic relationship with the mosquito host.
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