Evidence map›Paper›PMID 24842106›Full record

ReviewThe international journal of biochemistry & cell biology2014

Mitophagy mechanisms and role in human diseases.

Matthew Redmann, Matthew Dodson, Michaël Boyer-Guittaut, Victor Darley-Usmar, Jianhua Zhang

Abstract readReview
In one paragraph

Review in The international journal of biochemistry & cell biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Dynamic insights into mitochondrial function: Monitoring viscosity and SOJournal of photochemistry and photobiology. B, Biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Pharmacological Progress of Mitophagy Regulation.Current neuropharmacology · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew RedmannCenter for Free Radical Biology, University of Alabama at Birmingham, USA; Department of Pathology, University of Alabama at Birmingham, USA.
Matthew DodsonCenter for Free Radical Biology, University of Alabama at Birmingham, USA; Department of Pathology, University of Alabama at Birmingham, USA.
Michaël Boyer-GuittautUniversité de Franche-Comté, Laboratoire de Biochimie, EA3922, SFR IBCT FED4234, Sciences et Techniques, 16 route de Gray, 25030 Besançon Cedex, France.
Victor Darley-UsmarCenter for Free Radical Biology, University of Alabama at Birmingham, USA; Department of Pathology, University of Alabama at Birmingham, USA.
Jianhua ZhangCenter for Free Radical Biology, University of Alabama at Birmingham, USA; Department of Pathology, University of Alabama at Birmingham, USA; Department of Veterans Affairs, Birmingham VA Medical Center, AL 35294, USA. Electronic address: zhanja@uab.edu.

Funding

Sex hormones and arthritis in a long lived animal modelP30AG050886 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jianhua Zhang · 2015 to 2026
$11.3M
Alpha-synuclein degradation mechanismsR01NS064090 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHANG, JIANHUA · 2010 to 2014
$1.6M
NIA NIH HHS P30 AG050886NINDS NIH HHS R01 NS064090NINDS NIH HHS R01-NS064090
6 · The paper itself

Abstract

Mitophagy is a process of mitochondrial turnover through lysosomal mediated autophagy activities. This review will highlight recent studies that have identified mediators of mitophagy in response to starvation, loss of mitochondrial membrane potential or perturbation of mitochondrial integrity. Furthermore, we will review evidence of mitophagy dysfunction in various human diseases and discuss the potential for therapeutic interventions that target mitophagy processes.

Indexed as

Heart DiseasesHumansMembrane Potential, MitochondrialMitophagyNeoplasmsParkinson DiseaseCancerHeart diseaseMitochondriaMitophagyParkinson's disease

Identifiers

PMID24842106
PMCPMC4111979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.