Evidence map›Paper›PMID 24841557›Full record

SynthesisJournal of general internal medicine2014

Effectiveness of family and caregiver interventions on patient outcomes in adults with cancer: a systematic review.

Joan M Griffin, Laura A Meis, Roderick MacDonald, Nancy Greer, Agnes Jensen, Indulis Rutks, Timothy J Wilt

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of general internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06991673 (Adolescent Surgery Roadmap Feasibility and Acceptability Study), which is not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06991673 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Adolescent Surgery Roadmap Feasibility and Acceptability Study

TypeinterventionalSponsorUniversity of MichiganRan2025 to 2029Enrolled100ConditionsPediatric Surgical ProceduresArmsBehavioral Treatment
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Cancer patient distress and health service use is linked with carer distress: evidence from a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  4. Association between dyadic interventions and outcomes in cancer patients: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
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  12. A Methodological Approach for Documenting Multi-Component Interventions Targeting Family Caregivers.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023
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  13. Prospective assessment of psychopathological symptoms and their relation to demographic factors in primary caregivers of cancer patients throughout chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joan M GriffinCenter for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, One Veterans Drive, Mailstop 152, Minneapolis, MN, 55417, USA, Griffin.joan@mayo.edu.
Laura A Meis
Roderick MacDonald
Nancy Greer
Agnes Jensen
Indulis Rutks
Timothy J Wilt
Minneapolis VA Health Care System · USUniversity of Minnesota Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFamily and caregiver interventions typically aim to develop family members' coping and caregiving skills and to reduce caregiver burden. We conducted a systematic review of published randomized controlled trials (RCTs) evaluating whether family-involved interventions improve patient outcomes among adults with cancer.

methodsRCTs enrolling patients with cancer were identified by searching MEDLINE, PsycInfo and other sources through December 2012. Studies were limited to subjects over 18 years of age, published in English language, and conducted in the United States. Patient outcomes included global quality of life; physical, general psychological and social functioning; depression/anxiety; symptom control and management; health care utilization; and relationship adjustment.

resultsWe identified 27 unique trials, of which 18 compared a family intervention to usual care or wait list (i.e., usual care with promise of intervention at completion of study period) and 13 compared one family intervention to another individual or family intervention (active control). Compared to usual care, overall strength of evidence for family interventions was low. The available data indicated that overall, family-involved interventions did not consistently improve outcomes of interest. Similarly, with low or insufficient evidence, family-involved interventions were not superior to active controls at improving cancer patient outcomes. DISCUSSION: Overall, there was low or insufficient evidence that family and caregiver interventions were superior to usual or active care. Variability in study populations and interventions made pooling of data problematic and generalizing findings from any single study difficult. Most of the included trials were of poor or fair quality.

Indexed as

CaregiversFamilyPatient AdvocacyProfessional-Family RelationsAdultEarly Medical InterventionHumansNeoplasmsRandomized Controlled Trials as TopicTreatment Outcome

Identifiers

PMID24841557
PMCPMC4139519
OpenAlexW2017807127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.