ArticleAllergy2014
The relation of airway obstruction to asthma, chronic rhinosinusitis and age: results from a population survey of adults.
Article in Allergy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Assessment of Correlation Between Disease Specific Quality of Life and Endoscopy Score After 1 Month and 6 Months of Endoscopic Sinus Surgery (ESS) in Patients with Chronic Rhinosinusitis: A Prospective Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Comorbid asthma in patients with chronic rhinosinusitis with nasal polyps: did dupilumab make a difference?BMC pulmonary medicine · 2023Article
- Time-Specific Factors Influencing the Development of Asthma in Children.Biomedicines · 2022Review
- Expression of Transcript Variants ofDiagnostics (Basel, Switzerland) · 2021Article
- Determinants of persistent asthma in young adults.European clinical respiratory journal · 2018Article
- Reduced Forced Vital Capacity in an African Population. Prevalence and Risk Factors.Annals of the American Thoracic Society · 2017Article
- Potential application of injectable chitosan hydrogel treated with siRNA in chronic rhinosinusitis therapy.Molecular medicine reports · 2015Article
- Revisiting early intervention in adult asthma.ERJ open research · 2015Review
- Epidemiology of chronic rhinosinusitis, selected risk factors, comorbidities, and economic burden.GMS current topics in otorhinolaryngology, head and neck surgery · 2015Review
- Remembering the forgotten non-communicable diseases.BMC medicine · 2014Article
- Study on factors associated with post bronchodilator reversibility among patients presenting with dyspnea: An experience at a tertiary care academic hospital in Kerala.Lung India : official organ of Indian Chest SocietyArticle
Corrections and comments
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Authors and funding
23 authors at 17 institutions in 12 countries.
Funding
Abstract
rationaleThere is conflicting evidence on whether patients with asthma experience an accelerated decline in lung function with age. We examined the association between postbronchodilator lung function, asthma, chronic rhinosinusitis (CRS), and atopy with age using a large European sample.
methodsIn 17 centers in 11 European countries, case-control studies were nested within representative cross-sectional surveys of adults aged less than 75 years. Representative samples of participants with asthma, CRS or both and controls were assessed for postbronchodilator ventilatory function, smoking history, atopy, and treatment. Multiple regression was used to assess the interactive effects of age and diagnostic group on decline in postbronchodilator ventilatory function.
resultsA total of 3337 participants provided adequate data (778 with asthma, 399 with CRS, 244 with both asthma and CRS and 1916 controls who had neither asthma nor CRS). Participants with asthma had lower FEV1 /FVC (-4.09% (95% CI: -5.02, -3.15, P < 0.001) and a steeper slope of FEV1 /FVC against age (-0.14%/annum [95%CI: -0.19, -0.08]) equivalent to smoking 1-2 packs of cigarettes per day. Those with atopy had a slope equivalent to controls.
conclusionsPeople with asthma have a steeper decline in postbronchodilator lung function with age, but neither CRS nor atopy alone were associated with such decline.
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Registered trials
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