ReviewNature immunology2014
Immune diseases caused by mutations in kinases and components of the ubiquitin system.
Review in Nature immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Thirteen New Patients ofChildren (Basel, Switzerland) · 2024Article
- SARS-CoV-2/COVID-19 and its relationship with NOD2 and ubiquitination.Clinical immunology (Orlando, Fla.) · 2022Review
- Integrative Proteomic Analysis of Multiple Posttranslational Modifications in Inflammatory Response.Genomics, proteomics & bioinformatics · 2022Article
- Penta-o-galloyl-beta-d-Glucose (PGG) inhibits inflammation in human rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis model.Frontiers in immunology · 2022Article
- Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach.Journal of enzyme inhibition and medicinal chemistry · 2021Article
- Review
- PP2A and Its Inhibitors in Helper T-Cell Differentiation and Autoimmunity.Frontiers in immunology · 2021Review
- High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry-based deubiquitylating enzyme assay for drug discovery.Nature protocols · 2020Article
- Comparative Assessment of Protein Kinase Inhibitors in Public Databases and in PKIDB.Molecules (Basel, Switzerland) · 2020Article
- MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling.Nature communications · 2019Article
- The Ubiquitin Code of NODs Signaling Pathways in Health and Disease.Frontiers in immunology · 2019Review
- Tumour necrosis factor signalling in health and disease.F1000Research · 2019Review
- Geoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review.Clinical reviews in allergy & immunology · 2018Review
- Oncogenes in immune cells as potential therapeutic targets.ImmunoTargets and therapy · 2018Review
- Assembly and regulation of ASC specks.Cellular and molecular life sciences : CMLS · 2017Review
- Lessons from characterization and treatment of the autoinflammatory syndromes.Current opinion in rheumatology · 2017Review
- From the research laboratory to the database: the Caenorhabditis elegans kinome in UniProtKB.The Biochemical journal · 2017Review
- Lighting Up T Lymphocyte Signaling with Quantitative Phosphoproteomics.Frontiers in immunology · 2017Review
- Cellular and molecular regulation of innate inflammatory responses.Cellular & molecular immunology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The signaling networks that control the immune system are coordinated by a myriad of interconnecting phosphorylation and ubiquitylation events. This review provides an overview of mutations in human genes encoding these proteins that give rise to immune diseases. Analysis of the biological effects of these mutations has revealed the true physiological roles of particular signaling networks and promises to revolutionize the treatment of these diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.