ReviewNature reviews. Neurology2014
Ophthalmic manifestations of inherited neurodegenerative disorders.
Review in Nature reviews. Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 42 citations in OpenAlex.
- The Retina in Patients With Triple A Syndrome: A Window Into Neurodegeneration?Frontiers in endocrinology · 2021Trial
- Cancer-Associated Retinopathy Presenting with Paraneoplastic Cerebellar Degeneration in Tonsillar Squamous Cell Carcinoma: A Case Report.Reports (MDPI) · 2026Article
- Severe Dry Eye Disease in Charcot-Marie-Tooth Disease: A Comprehensive Case Report.The American journal of case reports · 2023Article
- Genipin relieves diabetic retinopathy by down-regulation of advanced glycation end products via the mitochondrial metabolism related signaling pathway.World journal of diabetes · 2023Article
- MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.iScience · 2023Article
- The New Zealand Genetic Frontotemporal Dementia Study (FTDGeNZ): a longitudinal study of pre-symptomatic biomarkers.Journal of the Royal Society of New Zealand · 2023Article
- Retinal and Visual Pathways Involvement in Carriers of Friedreich's Ataxia.Diagnostics (Basel, Switzerland) · 2022Article
- A novel homozygous variant in theAmerican journal of ophthalmology case reports · 2022Article
- Neurophysiological and ophthalmological findings of SPG7-related spastic ataxia: a phenotype study in an Irish cohort.Journal of neurology · 2021Article
- A Proposal for Classification of Retinal Degeneration in Spinocerebellar Ataxia Type 7.Cerebellum (London, England) · 2021Observational
- Clinical Characteristics, Differential Diagnosis and Genetic Analysis of Concentric Retinitis Pigmentosa.Life (Basel, Switzerland) · 2021Article
- Computer Vision for Brain Disorders Based Primarily on Ocular Responses.Frontiers in neurology · 2021Article
- Ophthalmic Manifestations and Genetics of the Polyglutamine Autosomal Dominant Spinocerebellar Ataxias: A Review.Frontiers in neuroscience · 2020Review
- An Assessment of Retinal Nerve Fiber Layer Thickness in Non-Diabetic Obese Children and Adolescents.Journal of clinical research in pediatric endocrinology · 2018Article
- Acute vitreoretinal trauma and inflammation after traumatic brain injury in mice.Annals of clinical and translational neurology · 2018Article
- Clinical Trial Designs and Measures in Hereditary Spastic Paraplegias.Frontiers in neurology · 2018Review
- Vision Loss in a Teenage Girl With Postconcussion Syndrome.JAMA ophthalmology · 2017Article
- Spectropathology-corroborated multimodal quantitative imaging biomarkers for neuroretinal degeneration in diabetic retinopathy.Clinical ophthalmology (Auckland, N.Z.) · 2017Article
- Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Ocular and neurodevelopmental features of Duchenne muscular dystrophy: a signature of dystrophin function in the central nervous system.European journal of human genetics : EJHG · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ophthalmic findings are common features of neurodegenerative disorders and, in addition to being clinically important, have emerged as potentially useful biomarkers of disease progression in several conditions. Clinically, these visual system abnormalities can be a clue to diagnosis, as well as being a prominent cause of disability in affected patients. In this Review, we describe the various afferent visual system and other ophthalmic features of inherited neurodegenerative disorders, including the muscular dystrophies, Friedreich ataxia, the spinocerebellar ataxias, hereditary spastic paraplegia, Charcot-Marie-Tooth disease, and other conditions. We focus on the expanding role of optical coherence tomography in diagnostic imaging of the retina and optic nerve head, and the possible use of ophthalmic findings as biomarkers of disease severity in hereditary neurodegenerative disorders. In addition, we discuss the ophthalmic manifestations and treatment implications of mitochondrial dysfunction, which is a feature of many inherited neurodegenerative diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.