ArticleJournal of neurogastroenterology and motility2014
Association between gastroesophageal reflux disease after pneumatic balloon dilatation and clinical course in patients with achalasia.
Article in Journal of neurogastroenterology and motility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 14 citations in OpenAlex.
- Comparative Evaluations on Real-Time Monitoring of Temperature Sensors during Endoscopic Laser Application.Sensors (Basel, Switzerland) · 2023Article
- Postoperative Dysphagia Following Esophagogastric Fundoplication: Does the Timing to First Dilation Matter?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Esophageal POEM: the new standard of care.Translational gastroenterology and hepatology · 2020Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThe occurrence of gastroesophageal reflux disease (GERD) is known to be associated with lower post-treatment lower esoph-ageal sphincter pressure in patients with achalasia. This study aimed to elucidate whether GERD after pneumatic balloon dilata-tion (PD) has a prognostic role and to investigate how the clinical course of GERD is.
methodsA total of 79 consecutive patients who were first diagnosed with primary achalasia and underwent PD as an initial treatment were included in this retrospective study. Single PD was performed using a 3.0 cm balloon. The patients were divided into two groups: 1) who developed GERD after PD (GERD group) and 2) who did not develop GERD after PD (non-GERD group). GERD was defined as pathological acid exposure, reflux esophagitis or typical reflux symptoms.
resultsTwenty one patients (26.6%) developed GERD after PD during follow-up. There were no significant differences between the two groups in demographic or clinical factors including pre- and post-treatment manometric results. All patients in GERD group were well responsive to maintenance proton pump inhibitor therapy including on demand therapy or did not require maintenance. During a median follow-up of 17.8 months (interquartile range, 7.1-42.7 months), achalasia recurred in 15 pa-tients (19.0%). However, the incidence of recurrence did not differ according to the occurrence of GERD after PD.
conclusionsGERD often occurs after even a single PD for achalasia. However, GERD after PD is well responsive to PPI therapy. Our data suggest that GERD after PD during follow-up does not appear to have a prognostic role.
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