Evidence map›Paper›PMID 24840093›Full record

ArticleJournal of the International Neuropsychological Society : JINS2014

Relationship between depressive symptoms and cognition in older, non-demented African Americans.

Jamie L Hamilton, Adam M Brickman, Rosalyn Lang, Goldie S Byrd, Jonathan L Haines, Margaret A Pericak-Vance, Jennifer J Manly

Open access · greenAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Anxiety symptoms bias memory assessment in older adults.International journal of geriatric psychiatry · 2017
    Trial
  2. Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Psychosocial Function in Mild Cognitive Impairment: Social Participation is Associated With Cognitive Performance in Multiple Domains.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  4. Depression Symptoms Moderate Associations between Daily Functioning and Neuropsychological Performance in Mexican American Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
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  9. Higher Comorbidity Burden Predicts Worsening Neurocognitive Trajectories in People with Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  10. Review
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  16. The Paradoxical Impact of Companionship on the Mental Health of Older African American Men.The journals of gerontology. Series B, Psychological sciences and social sciences · 2018
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jamie L Hamilton1Taub Institute for Research on Alzheimer's Disease and the Aging Brain,College of Physicians and Surgeons,Columbia University,New York,New York.
Adam M Brickman1Taub Institute for Research on Alzheimer's Disease and the Aging Brain,College of Physicians and Surgeons,Columbia University,New York,New York.
Rosalyn Lang5North Carolina Agricultural and Technical State University,Department of Biology,Greensboro,North Carolina.
Goldie S Byrd6North Carolina Agricultural and Technical State University,Dean,College of Arts and Sciences,Greensboro,North Carolina.
Jonathan L Haines7Center for Human Genetics Research,Vanderbilt University,Nashville,Tennessee.
Margaret A Pericak-Vance8John P. Hussman Institute for Human Genomics,Miller School of Medicine,University of Miami,Miami,Florida.
Jennifer J Manly1Taub Institute for Research on Alzheimer's Disease and the Aging Brain,College of Physicians and Surgeons,Columbia University,New York,New York.
Columbia University · USDean College · USNorth Carolina Agricultural and Technical State University · USUniversity of Miami · USVanderbilt University · US

Funding

Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Genetic Epidemiology of Alzheimer's Disease in African AmericansR01AG028786 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANLY, JENNIFER JAIE · 2007 to 2011
$7.3M
Research Training in Late-Life NeuroPsychiatric DisordersT32MH020004 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Patrick J Brown · 1998 to 2026
$6.1M
White matter hyperintensities in Aging and DementiaR01AG034189 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRICKMAN, ADAM M · 2010 to 2014
$2.0M
NCATS NIH HHS UL1TR000040NIA NIH HHS R01 AG028786NIA NIH HHS R01 AG034189NIMH NIH HHS T32 MH020004
6 · The paper itself

Abstract

Knowledge of the relationship between depressive symptoms and cognition in older adults has primarily come from studies of clinically depressed, functionally impaired or cognitively impaired individuals, and in predominately White samples. Limited minority representation in depression research exposes the need to examine these associations in more ethnic/racially diverse populations. We sought to examine the relationship between depressive symptoms and cognition in a sample of non-demented older African Americans recruited from surrounding U.S. cities of New York, Greensboro, Miami, and Nashville (N=944). Depressive symptoms were evaluated with the Geriatric Depression Scale (GDS). Cognition was evaluated with a comprehensive neuropsychological battery. Test scores were summarized into attention, executive function, memory, language, and processing speed composites. Controlling for age, education, reading level, and sex, African American older adults who endorsed more symptoms obtained significantly lower scores on measures of memory, language, processing speed, and executive functioning. Further investigation of the causal pathway underlying this association, as well as potential mediators of the relationship between depressive symptoms and cognitive test performance among older African Americans, such as cardiovascular and cerebrovascular disease, may offer potential avenues for intervention.

Indexed as

AgingAgedAged, 80 and overBlack or African AmericanCognition DisordersDepressionFemaleGeriatricsHumansMaleNeuropsychological TestsPsychiatric Status Rating ScalesUnited States

Identifiers

PMID24840093
PMCPMC4142348
OpenAlexW2051668819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.