ReviewCurrent opinion in HIV and AIDS2014
Identifying the appropriate comparison group for HIV-infected individuals.
Review in Current opinion in HIV and AIDS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Greater ambient air pollution exposure is associated with worse respiratory symptoms in men and women with HIV and chronic lung disease: a cohort study.Respiratory research · 2025Article
- Correlates of Breakthrough SARS-CoV-2 Infections in People with HIV: Results from the CIHR CTN 328 Study.Vaccines · 2024Article
- Article
- Disparities in multimorbidity and mortality among people living with and without HIV across British Columbia's health regions: a population-based cohort study.Canadian journal of public health = Revue canadienne de sante publique · 2021Article
- Mortality Among Persons Entering HIV Care Compared With the General U.S. Population : An Observational Study.Annals of internal medicine · 2021Observational
- Negative Consequences of Alcohol Use among People Living with HIV.Substance use & misuse · 2021Article
- The Changing Science of HIV Epidemiology in the United States.American journal of epidemiology · 2019Review
- Cancer Risk in Older Persons Living With Human Immunodeficiency Virus Infection in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Multimorbidity Among Persons Living with Human Immunodeficiency Virus in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Elevated Markers of Vascular Remodeling and Arterial Stiffness Are Associated With Neurocognitive Function in Older HIV+ Adults on Suppressive Antiretroviral Therapy.Journal of acquired immune deficiency syndromes (1999) · 2017Article
- Aging and HIV: an evolving understanding.Current opinion in HIV and AIDS · 2014Article
- Accounting for HIV Health Disparities: Risk and Protective Factors Among Older Gay and Bisexual Men.Journal of aging and healthArticle
- Excess Clinical Comorbidity Among HIV-Infected Patients Accessing Primary Care in US Community Health Centers.Public health reports (Washington, D.C. : 1974)Article
- Social, Economic, and Health Disparities Among LGBT Older Adults.Generations (San Francisco, Calif.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purpose of reviewHIV-infected individuals are living longer as a result of effective treatment. Age-related comorbidities now account for the majority of morbidity and mortality among treated HIV-infected adults. Previous findings regarding the age at, and risk of, these comorbidities have been mixed, sparking debate in the field. Discerning potential differences in the occurrence and burden of age-related comorbidities among treated HIV-infected adults as compared with uninfected adults of the same age requires careful selection of the appropriate uninfected comparison group. RECENT
findingsThe validity of comparisons with HIV-uninfected populations is threatened when differences in demographic, clinical, and lifestyle characteristics between HIV-infected and uninfected adults are not considered. Identifying a pool of HIV-uninfected individuals from existing secondary data resources and employing selection methodologies may be a novel approach to reduce threats to internal validity. Issues related to identifying data sources, understanding inclusion criteria, determining measurement error, and threats to inference are discussed. SUMMARY: The development of clinical interventions targeting age-related comorbidities will rely on deriving valid inferences from appropriate comparison groups. The use of secondary data resources and selection methodology to create the appropriate uninfected comparison group is an attractive approach in the setting of finite resources, but are not without limitations.
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Registered trials
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