ArticleJournal of veterinary internal medicine
Corpus callosal abnormalities in dogs.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Severe Hypernatraemia Secondary to Adipsia Associated With a Pituitary Macroadenoma in a Dog: A Case Report.Veterinary medicine and science · 2026Article
- Article
- Hypernatremia, Hyperlipemia and Hemorrhagic Enteritis in a Hypodipsic Dog with Corpus Callosum Dysplasia.Animals : an open access journal from MDPI · 2025Article
- Case Report: Hypodipsic hypernatremia secondary to hydrocephalus in a dog.Frontiers in veterinary science · 2025Article
- A diffusion tensor imaging white matter atlas of the domestic canine brain.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Hypodipsic hypernatremia after long-standing polydipsia in a cat with suspect neonatal head trauma.The Canadian veterinary journal = La revue veterinaire canadienne · 2023Article
- Bruxism in awake dogs as a clinical sign of forebrain disease: 4 cases.Journal of veterinary internal medicine · 2022Article
- Holoprosencephalia, hypoplasia of corpus callosum and cerebral heterotopia in a male belted Galloway heifer with adipsia.BMC veterinary research · 2022Article
- Aprosopia/holoprosencephaly in a stillborn puppy: when the face predicts the brain.International journal of veterinary science and medicine · 2021Article
- Aventriculi associated with holoprosencephaly in a dog.Journal of veterinary internal medicine · 2020Article
- Lobar holoprosencephaly with craniofacial defects in a Friesian calf: A case report.Veterinary medicine and science · 2020Article
- Lissencephaly in Shih Tzu dogs.Acta veterinaria Scandinavica · 2020Article
- A Deletion inGenes · 2020Article
- Magnetic Resonance Imaging and Histopathologic Findings From a Standard Poodle With Neonatal Encephalopathy With Seizures.Frontiers in veterinary science · 2020Article
- The use of diffusion tractography to characterize a corpus callosum malformation in a dog.Journal of veterinary internal medicine · 2019Article
- Presence of Probst Bundles Indicate White Matter Remodeling in a Dog With Corpus Callosum Hypoplasia and Dysplasia.Frontiers in veterinary science · 2018Article
- Successful treatment of hypodipsic/adipsic hypernatremia in a cat with lobar holoprosencephaly using oral desmopressin.JFMS open reportsArticle
- Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCorpus callosal abnormalities (CCA) in dogs have been only sporadically reported and are poorly characterized. HYPOTHESIS/
objectivesTo describe the clinical presentation and magnetic resonance imaging (MRI) characteristics of dogs with CCA. ANIMALS: Fifteen client-owned dogs.
methodsRetrospective study. Records of the contributing institutions were reviewed to identify dogs diagnosed with malformations affecting the corpus callosum (CC); cases in which the CCA was thought to be secondary were excluded.
resultsThe most represented breeds were Staffordshire Bull Terriers (5/15) and Miniature Schnauzers (3/15; n = 3, 20%) and the mean age at time of presentation of 19 months (range 3-81 months). The clinical signs most commonly reported were adipsia/hypodipsia with associated hypernatremia (12/15), tremors (6/15), and seizures (6/15). Review of the MR images revealed that 10 dogs had absence of the rostral CC and hypoplasia of the caudal portion, 4 dogs had a diffusely hypoplastic and dysplastic CC, and 1 dog had a diffusely hypoplastic CC. In 14 cases, there was abnormal cortical development with fusion of the ventral frontal lobes and part of the diencephalon, indicating lobar holoprosencephaly. CONCLUSIONS AND CLINICAL IMPORTANCE: Previous literature has mainly associated CCA with adipsia and only 12 of 15 dogs in the current series demonstrated this abnormality. There are different degrees of the malformation but in 10 dogs the rostral portion of the CC is most severely affected. Fourteen dogs have simultaneous fusion of the midline structures rostral to the CC; this region has several structures involved in thirst regulation and might explain this derangement.
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