ArticleInternational journal of body composition research2013
Atypical antipsychotic drugs inhibit trabecular bone accrual in C57BL/6J mice.
Article in International journal of body composition research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Olanzapine affects bone formation via oralFrontiers in cellular and infection microbiology · 2025Article
- Thermoneutral housing does not rescue olanzapine-induced trabecular bone loss in C57BL/6J female mice.Biochimie · 2023Article
- Novel report on congenital talipes equinovarus (CTEV) following olanzapine exposure during pregnancy: case report and short review.Archives of women's mental health · 2022Article
- Elucidating the Mechanism(s) Underlying Antipsychotic and Antidepressant-Mediated Fractures.Journal of mental health & clinical psychology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the effects of the atypical antipsychotics drugs (AADs), olanzapine and risperidone, on femoral bone characteristics in female C57BL/6J mice.
methodsMice were treated with placebo or AADs (olanzapine or risperidone) for 3-4 weeks. Femoral cortical and trabecular bone characteristics were determined using micro-computed tomography.
resultsOlanzapine-treated mice tended to have lower trabecular bone volume (
conclusionAADs inhibited trabecular bone accrual in C57BL/6J mice suggesting that alternative treatment options may need to be considered for the schizophrenia patient with potential osteoporosis risk.
Indexed as
Identifiers
24839401PMC4023556W185837325What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.